Lyrica Approved to Treat Fibromyalgia

On June 21 the FDA approved Lyrica (pregabalin) as the first drug specifically indicated to treat pain from fibromyalgia. Lyrica is an analgesic (pain relieving) and anit-convulsant medication that is also approved to treat chronic pain. The study results submitted to the FDA for approval showed that 30 to 60% of study participants experienced significant pain relief with Lyrica.

It is not known exactly how Lyrica works to reduce pain in patients with fibromyalgia. It is thought that the drug may effect how neurotransmitters (chemicals in the brain) transmit signals from one neuron to another.

The data submitted to the FDA were from two randomized, placebo-controlled trials of about 1800 adults. These trials showed that treatment with Lyrica in doses of 300-450 mg per day reduced pain and improved function in patients with Fibromyalgia, and symptoms became worse when the people stopped taking Lyrica.

There are a number of potential risks and side effects with Lyrica, including but not limited to dizziness and sleepiness, blurry vision, impaired motor function, weight gain, trouble concentrating, swelling of the hands and feet, dry mouth, and potential allergic reactions. Side effects, which are somewhat correlated with dosage, may be significant and impair one's ability to drive.

Source:

FDA website - lyrica approval

FDA consumer health information

Posted by: Stephanie