"An in-vivo study conducted by Buser et al in 2004 showed that around 70% of bone ongrowth occurs on roughened titanium surfaces within four weeks. Clinically, we have had Titan patients go back to manual labor in six weeks - which I would have not allowed my patients to do in the past. Longer term, a prospective study on our ALIF device has shown that our patients make significant gains in back and leg pain relief, as well as reductions in disability metrics, by 6 months. And these improvements have been shown to hold steady through two years post-op." Dr. Peter Ullrich. Read More...
- Initial stability: (micro surface stability) encourages a more stable fusion and potentially allows a faster return to normal activities; micro surface stability.
- Faster fusion: In-vitro data demonstrates a significantly greater bone formation response with the Titan Spine surface when compared to other common interbody materials, such as polyetheretherketone (PEEK) or smooth titanium.
- Good visualization allows surgeons to see how fusion is healing and when to give the okay to return to normal activities.
Dr. Gerard Girasole1 was the principle investigator for the journal article that evaluated OsteoSponge® for interbody fusion in conjunction with Titan Spine's Endoskeleton TT titanium cage and autograft bone. The study involved a set of patients evaluated at 6 months and a separate set of patients that were evaluated at 1 year post-op. An independent radiologist reviewed and graded the CT scans for evidence on fusion and determined the fusion rates to be 41 of 44 (93.2%) for the 6 month group and 37 of 38 (97.4%) for the 12 month group. There were no radiographic device-related complication. The International Journal of Spine Surgery, Volume 7, Issue 1, December 2013, Pages e95–e100
- Presentation at ISASS, April 3-6, 2013: A Prospective Study of a Unique Titanium Interbody Fusion Implant; Clinical and Radiographic Outcomes at 1 and 2 Year Follow Up.
- Olivares-Navarrete Study. The results show that modifying surface structure is sufficient to create an osteogenic environment without addition of exogenous factors, which may induce better and faster bone during interbody fusion.