I am almost 2 weeks since my L5- S1 microdiscectomy. I was still having so much irritation and pain in the nerve from my right buttock, hamstring that I called my neurosurgeon and he started me on a Medrol dose pack and Neurontin. The Neurontin 300mg is to be gradually started [one at bedtime for 5 days and then one two times a day for 5 days and then go to one 3 times a day]. I took my first one last night and this morning I was staggering. I am sure that I would get adjusted to it and if it is going to help me I want to keep taking it. Is anyone on it now? Does it help? How long before you noticed a change?