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MS Contin, anyone?

meydey321mmeydey321 Posts: 2,435
edited 06/11/2012 - 8:31 AM in Pain Medications
Hi everybody, I switched from fentanyl to morphine ER and I take 60mg 3x's a day and I am hoping to hear from anyone who has experience with it. Does it help with your chronic pain, and what side effects do you get? Thanks


  • Morphine works differently for each individual. I don't get good pain relief from morphine based drugs, and experience a lot of increased nausea and vomiting from it, so I don't take that type of pain med.
    I know that others get great relief from them, so it really is dependent upon how your body reacts to it.
    You may or may not experience some drowsiness and some nausea with it, at least in the beginning, but those may go away after a week or so on it. You may not have any problems with side effects at all, it depends on how your body is going to react, just like whether or not you will get decent pain coverage.
    Best of luck to you,
  • I've been on Avinza for just over a month (that's the name brand for MS-Contin), 30mg once per day. I have noticed NO side effects and there was noticeable relief the first day. Don't know if I am developing a dependence or if I've been overdoing it, seems like I'm using breakthrough meds fairly regularly these days.
  • So far I haven't experienced any side effects, and the last thing I want is to feel sick and toss my cookies. I'm still taking the six Percocets a day for breakthrough pain. I also know that it will take some time for the morphine to build up in my system so I can get some relief.
  • I was shocked that I had no real side effects. Any of the Hydro/Oxy narcotics make me take a nap in a hurry and the MS-Contin does not. All of a sudden I could go to work and make it through the whole day again. Next couple weeks will be the real test though, we've been so busy getting ready for our son to graduate that I've been overdoing it. Now it's time to relax a bit!! I'm hoping I can go back to only occasional use of BT meds in the next couple weeks.
  • Congratulations on your son's graduation <:P I know it means the world to you and I hope you feel great for this special day (and every other day too!)

    Right now I'm still having a good amount of pain and I think it's because I've been out today and there's a chance of rain of course.
  • Thank you, we're awful proud and had a graduation party this past weekend. <:P he'll be "leaving the nest" to Cali in August so we're a bit worried about that... I told him to make sure he has enough money to come back home (Denver), it may be tougher than he thinks.

    Oh, the rain... ugh. We've had rain here for past few days, and I've been doing so poorly. Usually for me it's the autumn season that makes me hurt more, I think it's getting to me now though too. My MS-Contin didn't work at all it seems yesterday (couldn't imagine if I hadn't taken it though!) I had to use my Vicodin and Tramadol both during the day yesterday. I sure hope today is better. The good news is that I think it's supposed to get sunny, I see another specialist on Thursday and today is the last day of my work week. Things are looking up!! :D

    I hope the MS-Contin works well for you, it's another one of those that affects everyone differently. Gives my wife horrible migraines and makes my mom itch like crazy. Guess we're lucky!!
  • I just wanted to add that Avinza is not the brand name for MS Contin. MS Contin is the brand name for a 12 hour extended release Morphine Sulfate. Avinza is Avinza and it is the only 24 hour modified release Morphine Sulfate and it comes in strengths of 30 mg, 60 mg, 90 mg, and 120 mg. It has no generic equivalent as of yet. I know this because I have been taking it for about 2 years now. I don't like the MS Contin anywhere near as much as the Avinza and that's probably because the Avinza lasts a lot longer for me. I think my Avinza lasts me about 20-30 hours depending on what I've eaten or done that day. The MS Contin only lasts me about 8 hours. I really like the Avinza if only for its pain relief aspects. Many people confuse strength with buzz and thats just wrong. Most folks that have been taking OxyContin for years and are switched over to a Morphine Sulfate like Avinza are not happy with it because one, it hits a different receptor in the brain and two, it releases only 10% of the drug every hour so it keeps you at the same level. There's no highs and lows, ups and downs, etc. Yet, the drug keeps you pain free. MS Contin is the same type of drug only it releases like OxyContin only its Morphine Sulfate. If you're taking 180 mgs of MS Contin a day, that may not be enough for you. Fentanyl is a much stronger drug. You may want to talk to your PM Dr.
  • herrball, thanks for that clarification, you are correct on those distinctions. Oh boy, I sure like the extended release of the Avinza over what I've done in the past!
  • Hey buddy,

    How's things going? I just wanted to let you know that my new pain mgmt doc increased my mscontin to 3x/day about 6 weeks ago and I really don't see a difference. I don't feel that much pain releif from it as I did from taking 6-8 vicodin a day. The only thing I like about it is that I'm only taking 3 pills a day instead of 6-8 but I still have to take 1-2 vicodin per day. I'm starting to wean off the mscontin by my own choice cuz it doesn't seem to be helping so I'm down to twice a day and don't really see a difference if I take 2 or 3. I'm also weaning off the gabapentin which I started on Friday.

    I hope you find some pain releif soon.

    Take care my friend.
  • Be careful with the Vicodin. You don't want too much tylenol/APAP going into your system on a daily basis for long periods of time. It's just not good for the liver. So, be careful with the vicodin, hydro, norco, lortab, lorcet, zydone, etc. All of those hydrocodone based drugs. They all have aspirin in them or tylenol.
  • Hi Herrball, you're right about the morphine dosage. I am coming from taking 100 mcg's of Fentanyl. My morphine dose was calculated and I read somewhere that you're not started at the highest equivalent in fear of causing side effects like trouble breathing. They prefer to dose you like 20% under what you would normally be at, and then work it up after.

    Hi Ming, I'm glad your doctor was willing to raise the morphine but am sorry it didn't help. Can he give you something else like Oxycontin, Fentanyl, Methadone, or Opana? I know there's something efficient out there for you. I'm allowed only 6 percocets a day and this is because of its tylenol content. So far I'm still having a lot of pain and I rely on both meds to get me through this.

    Thank you again for all your help :H
  • Instead of percocet, have you Dr give you oxycodone, it is percocet without tylenol. Thats what I take for BT with fentanyl. Just for you info.
  • My bottle says oxycodone/apap and I know it has tylenol. I always thought that it would make the oxycodone portion work better (forgot the term for that). I also am worried about how to ask for straight oxycodone; I wouldn't want to be misinterpreted in any way. And on top of everything else, I am waiting to have surgery to permanently implant a morphine pump. It's hard to wait when you're having a lot of pain but I look forward to getting better relief.
  • I've been on MS Contin generic for 2+ years for my chronic pain and it's worked magnificently. I was switched to Fentanyl for a rotation to reduce my tolerance and that didn't work at all for me.

    I went from 60mg 3x daily a couple months ago and am now on 30mg 3x daily, and it works great.

    meydey, if you want to ask for just Oxycodone, cite the liver problems associated with tylenol use in large quantities over time. Usually doctors take that into account and mine always have.
  • i have had nothing but good luck with the use of the medication!! =D> i take the same as your dose and it has helped the pain in my back more than anything i have ever taken. <:P i am on a pretty good pain regime right now.. i hope you have the same luck! :D give yourself time to get over the sleepiness! (|: your body will adjust! =D> Jenny
  • Thanks Chronic Pain1..I'm glad to hear that the morphine worked out so well for you. It's so true about tylenol wreaking havoc in your liver. I wonder how long someone can be on it before the damage starts. I heard if you stay under 4000 grams? a day that it is relatively safe. I've been taking Norco for 3 years straight and just recently switched to oxycodone/apap. I never had my liver checked.

    Thanks Jenny for your encouragement, and I'm glad you too are doing well with your meds.
  • My PM doc always puts me on a new medication for a week to try it out and see if it works, I'm glad they do.

    The Morphine works great for me(when I restarted there's some sleep issues, it keeps me awake and constipation) and a lot of the time I only need 2 a day when prescribed 3.
  • I just asked my pain dr if I could have the oxycodone withour tylenol because I didnt want to take that much tylenol all the time. It wasnt a problem.
  • ChronicPain1, that is really great your PM doctor does that for you. It seems you're at the right place. Anyway, I hadn't had issues with constipation or insomnia thank goodness. The Zanaflex always puts my lights out and I eat prunes and foods with fiber. I haven't resorted to a laxative in a long time :D

    Robin, it's great that you had no problem getting the straight oxycodone. I will consider asking when the time is right.
  • dr put me on morphine 30 er and 15 ir.didn;t work well for me.now i;m taking hydro-10-325 2 every 6 hours.seems to work better then the morphine.
  • I'm glad the Norco's do something for you. It'd be cool if they invented a long acting form of it. I used to take them but after 3 years I built a tolerance to them and then went on to oxycodone.
  • I was misdiagnosed for years inbetween combat tours. I had horrible headaches and around the clock neck pain. In Iraq there wasn't an MRI to be done so when I was diagnosed with Traumatic Brain Injury, Herniated Cervical Disc and DDD I was switched from short acting medications like Fiorcet and Codeine which I swore worked great but I did not like the "ups and downs" of the medication level to MS Contin and I was elevated eventually to 60mg MS Contin every 8 hours.
    And it provides the most extensive and long lasting "plateau" of pain relief I've ever had. From about two hours after first dose through the end of the day the medication level never alters.
    I don't feel high.
    I don't feel dopey.
    I am simply relieved of pain.
    I am going to be weaned off of it after some physical therapy but if it doesn't work and I still feel pain I feel quite confident that I will be able to be taken care of by the VA pain wise.
    I hope it works for you as well...
    take care
  • Welcome to SH :H I'm sorry you were hurt during combat duty, and we all appreciate the sacrifices you have made. It's good to hear that you're getting good treatment and the MS Contin is making a difference with your pain.

    I was shocked that there aren't any MRI's in Iraq; where you flown to somewhere like Germany for treatment? Well, I hope you'll be able to start PT soon, but remember to not push yourself too much. Did you have surgery for the herniated disc? Are you seeing a back specialist and pain doctor at the VA?

    Please take good care of yourself and best wishes on your recovery. <):)
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