i got a diagnosis about 18 months ago ("disc abnormalities at l4 l5 & ddd at l5 s1", which i think means they really have no idea what the problem is) & due to the kind of 24-7 unrelenting pain most of you are familiar with, i'm on 50 mg kadian per day with up to 20 mg a day of statex for breakthrough pain.
that's not where i started. a year ago, i was getting pain relief from a single 10 mg statex pill when the pain got really bad. now, to achieve that same relief, i need the kadian every day as well as 20 mg statex. & i'm getting breakthrough pain again that lasts all day, which means i'm on my way back to my pain specialist to talk about--probably--increasing the kadian.
this tolerance effect is kinda scaring me. i'm not sure if the arc of my increasing dosage is "normal" & i'm wondering what others' tolerances have been like on morphine. how often did you need to increase your dosage? did this effect slow down once you got to a certain dosage? how high can a dosage go? do you worry about what you'll have to be taking in 5 years to get the pain relief you're getting now? i would really appreciate hearing from anyone else who is using morphine for their pain management, especially if you've been taking it for more than a couple of years & in higher dosages.
the other thing i'm wondering, have you heard of anything that can be taken with the morphine to slow down the tolerance effect? i seem to remember reading something about...potassium, maybe?...& wonder if anyone has any info about this. i'm still trying to research this, & if i find anything i'll be sure to add it as a follow-up to this post.
anyway--i'm getting good relief from the morphine, with pain generally at a 3 or 4 when it's well-managed, & i feel lucky to have it as an option. very few side-effects except pain in my fingers in the morning & the dreaded constipation. but i'm a bit freaked out that i have to take more to get the same pain management--i know that's normal, but i'm really hoping to hear from some of you with more experience & knowledge of kadian, avinza & statex.
thanks so much. these forums & all the posts over the years are an amazing resource.