Probably not posted in right area but has anyone got some knowledge or personal experience in this area?
My personal circumstances and observations: I am a 50 year old male and have been in difficulty for nearly 4 weeks and prescribed OxyContin and full rest to give a herniated disk a chance to recover (reduce pressure on nerve root and was sent home alone in significant pain). While I think there is some improvement (can move now for a few minutes without significant pain) I am noticing sudden mood swings. One day feeling that definitely improving and the next morning (also feeling improvement) then suddenly show symptoms of clinical depression (start crying etc) around ½ hour before medication (OxyContin) but then settled down after an hour. I am definitely in less pain than 2 weeks ago but after moving around (going to physiotherapist) and experience some pain (definitely at lower level than in the past) also experience the signs of clinical depression but were immediately resolved with microwave meal. Being alone and substantially immobile, I am not cooking but having a coffee in morning with maybe 2 apples and some snacks (biscuits or slice apple pie) during the day and Microwave meal (Rice or Pasta basis or sometimes frozen Pizza) for dinner. My research below does not show any relationship but that is not what I think I am experiencing.
Research on the packaging information
I am in a country where the drug information is in a non-English language so looked up the OxyContin package insert in English (believe this is manufacturer page so hopefully mediator will leave in this posting) http://www.purduepharma.com/PI/Prescription/Oxycontin.pdf
The graphs on page 6 seem to show the drug starts having and impact around half hour after the tablet is taken (when swallowed in accordance with instructions). According to Page 5 it has a half life of 4.5 hours (and with half life expect residual effect after the 12 hours of slow release), and page 4 indicates “steady-state levels were achieved within 24-36 hours” so that all makes sense. The document states things like somnolence (sleep), respiratory depression and sudden release if chew causing heart problems etc. It also states “Such drugs are sought by drug abusers and people with addiction disorders and are subject to criminal” and variations of this statement in various parts.
The document does not cover its relationship to clinical depression so started to look elsewhere. Looking at various web sites they indicate OxyContin is capable of giving a high (when crushed and snorted etc i.e. large quick does) but I take it per recommendation but certainly mood swings could be possible. I was also told by my doctor (but did not seem to be on the manufacturers’ document) that it suppresses appetite and to manage one of the documented side effects prescribed stool softeners.
Incidentally feeling a little worse in terms of muscle and pain but better in terms of mood (signs of depression) today so reinforces the opinion that personal physical assessment is not correlated with the personal mental assessment.
I am a Native English Speaker currently stuck in a foreign country so while communication with doctor is good it is not ideal. If someone knows where I can find more information (send me links personally if required) and experience or information will be appreciated.
Kind Regards to all out there.