Welcome, Friend!

It looks like you're new here. If you want to get involved, click one of these buttons!

Veritas-Health LLC has recently released patient forums to our Arthritis-Health web site.

Please visit http://www.arthritis-health.com/forum

There are several patient story videos on Spine-Health that talk about Arthritis. Search on Patient stories
Protect anonymity
We strongly suggest that members do not include their email addresses. Once that is published , your email address is available to anyone on the internet , including hackers.

Notice
All discussions and comments that contain an external URL will be automatically moved to the spam queue. No external URL pointing to a medical web site is permitted. Forum rules also indicate that you need prior moderator approval. If you are going to post an external URL, contact one of the moderators to get their approval.
Attention New Members
Your initial discussion or comment automatically is sent to a moderator's approval queue before it can be published.
There are no medical professionals on this forum side of the site. Therefore, no one is capable or permitted to provide any type of medical advice.
This includes any analysis, interpretation, or advice based on any diagnostic test

New Medication approved by the FDA

sandisandi Posts: 6,448
edited 06/11/2012 - 8:35 AM in Pain Medications
There is a new pain medication that has been approved by the FDA. It's trade name is Embeda- it is an extended release morphine sulfate pill with naltrexone in it to prevent people from crushing or chewing them.
Here is the website for it- http://www.drugs.com/embeda.html
advertisement

Comments

  • I hope not, for your sake. Morphine makes me sick to my stomach, so I don't think mine will try that with me, but you never know. They did with the Opana and it was a huge waste of money, and had little pain relief with it, not to mention the stomach issues.
    Sandi
  • I just want to point out that the naltrexone is in the pills not to stop you from crushing or chewing it but for people to IV the medication.

    Although this really doesn't work all that well because there is naltrexone in Suboxone as well but people still IV it all the time. I believe it was demark or sweden that actually has more people using suboxone IV than heroin and they confiscated more suboxone off the street than cocaine or heroin, which is kind of facinating to me.

    But even if there was a good sized dose of naltrexone in that morphine pill it only last about 5 minutes max at which point the morphine will kick in anyway so I really really do not see what these drug companies are trying to do.

    For instance, if you were to be taken to the hospital for an opiod overdose (hypothetically of course) they would not just give you one shot of narcan and send you on your way. You must be on a continual IV infusion for 4-6 until the drug you took is out of your system.

    Sorry for the rant but all of this 'new' medication that just has naltrexone (narcan) in it is just a way for them to get a new patent on an extremely old drug to keep charging people up the ass for it when it was discovered 200 years ago...........

    EDIT: I forgot to mention, the naltrexone is inactive orally so if you were to crush the pill and then eat it it would still work just as well as a pill with out the new medication, thusly, my point on IV use is the main concern here.
  • I have to disagree with what you wrote about the naltrexone being in the morphine sulfate to prevent IV drug use, it says specifically on the website link if you read it at all, that Embeda contains natrexone hydrochloride that will be released if the pill is crushed or chewed./b> It says nothing about IV use.
    I copied the relevent information from the website so that others can read it for themselves.
    Before putting information like what you wrote on internet as fact, please read the information about the medication because you could be giving out the wrong information.
    Sandi

    Embeda contains extended-release morphine pellets, each with an inner core of naltrexone hydrochloride, an opioid receptor antagonist. If taken as directed, the morphine relieves pain while the sequestered naltrexone hydrochloride passes through the body with no intended clinical effect. The clinical significance of the degree of this reduction has not been established, and there is no evidence that the naltrexone in Embeda reduces the abuse liability of Embeda.

    Important Safety Information for Embeda
    Embeda (morphine sulfate and naltrexone hydrochloride) Extended Release Capsules is a prescription medicine used to treat moderate to severe pain that continues around the clock and is expected to last for a long period of time. Embeda is not for use to treat pain as needed. Embeda contains morphine a Schedule II controlled substance. Morphine is a strong opioid pain medicine that can be abused by people who abuse prescription medicines or street drugs. Embeda contains beadlike pellets that are made up of morphine sulfate, an opioid receptor agonist (narcotic pain medicine), and naltrexone hydrochloride (HCl), an opioid receptor antagonist. The naltrexone hydrochloride within each pellet is confined or sequestered and has a special coating to protect it from being released. Embeda is to be swallowed whole or the contents of the capsules sprinkled on apple sauce. Do not crush, dissolve, or chew Embeda or the pellets in the capsules. If tampered with by crushing or chewing, the naltrexone will be released.
  • I am sorry I read naloxone not naltrexone.

    But mitigating IV use of pills is still a top priority of adding these kinds of things.
  • I don't disagree that there is a huge movement to prevent IV use, but there are far less IV drug users than ones who snort/sniff or otherwise try to find new ways of getting high despite whatever protections are put in place.
    Sandi :)
  • The naltrexone is just an opiate blocker. If the medication is IV injected it blocks the opiate in the meds so if anything else injected with the opiate will not react with it and cause a reaction resulting in overdose. When crushed and swallowed the naltrexone is not absorbed in the stomach and simply excreted out of the body. It's the same thing they put in Suboxone. Due to the fact a some people in Europe crushed Bupenepherine and Valium and injected them resulting in overdose the FDA would only approve bupenepherine(a partial opiate) to treat opiate addiction if naltrexone was combined with it thus creating Suboxone.
  • If you would have read my prior post and the OPs response you would notice that you too are talking about naloxone not naltrexone. Naltrexone is active orally and for 4-6 hours unlike naloxone (which is in suboxone). Naltrexone is also used to help alcoholics not drink because drinking with naltrexone causes very bad side effects.

    I even made this mistake but you should read the whole thread before posting!
  • Apparently we're BOTH human. Sorry for the mistake DAD!!! I don't appreciate the tone in your last sentence you xxx especially since you admitted to making the same mistake.

    Post edited to remove foul language. If this continues you will be banned from this site

    Ron DiLauro, Spine-Health Administrator 09/21/09
  • I'm sorry, I didn't mean to have such 'tone' i was just saying...

    I agree, we are both the same species
  • I apologize for being testy. I will pay attention to the posts in the future.
  • I apologize for being testy. The only question I have is is the word I used truly classified as a foul word?
advertisement
Sign In or Register to comment.