I came across your messages as I was trying to find out more about Nucynta & Opana ER, which are the pain meds my new pain specialist put me on. I relocated to another state & had to get new doc. He took me off Avinza 120 mg & these new drugs leave me in agony & unable to sleep. I don't find them effective.
My prior docs needed me off Tylenol based & codeine meds and showed me encouraging data on Avinza, an extended release morphine, which indicated a very consistent level of medication in your body over a 24 hour period. It worked very well for me. I liked that I took only ONE pain pill a day and all the ups & downs of past meds were gone. There was no euphoria or "high" where you felt tons better followed by a "low" from the recurrence of pain few hours later like other meds that wear off. I wasn't constantly thinking about next doses of meds, feeling crappy when I was busy & forgot a dose, or in pain wishing time would speed up so I could take the next dose because my liver metabolizes everything else quickly after 15 years of pain meds. For me, I never "felt" Avinza working-it just took away the pain without highs & lows.
I have tried everything mentioned on these boards & am happiest with how Avinza keeps consistent levels of meds with only one dose every 24 hours. That also meant I didn't have to carry around such strong meds
By the way, anyone familiar with fentanyl patch problems? I tried those for awhile, but was allergic. Now I keep seeing these ads on tv for class-action lawsuits on behalf of those who have died using the patch. Now I guess my allergy wasn't such a bad thing.