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Cervical Fusion and BMP

AnonymousUserAAnonymousUser Posts: 49,671
edited 06/11/2012 - 8:35 AM in Back Surgery and Neck Surgery
I had ACDF on c6-7 on March 31, 2009. In May and early June, all was going well but then the pain and numbness started again. In July, x-rays showed the the donor bone was being absorbed by my body. In 6 weeks it had lost 1/2 its height and it was becoming clearer on the x-ray. 6 weeks later, new x-rays showed further donor bone loss and the space between c6 and c7 is almost gone. The doctor wandt to go in again, but this time he plans on using a plastic spacer with a sponge soaked in BMP in the middle of the spacer. This is supposed to encourage my own bone to grow through the sponge like is would donor bone while allowing the height of the space to stay because of the plastic spacer.

Has anyone here had BMP used cervically? I have read great things about its use in lower back issues but the warnings on cervical issues scare me more than the surgery does.


  • ERNurse has many posts on this topic. Run a search and you will find links to all kinds of information and study.

    Here is one I ran across that talks about the ongoing clinical trials: http://www.necksurgery.com/articles-infuse_clinical_trial.html

    and a bit from another study:

    Caution should be exercised with rh-BMP-2 use in ACDF surgery as the correct dose and technique for application is not yet determined. Respiratory distress and dysphagia may result secondary to rh-BMP-2 induced anterior neck swelling.

    It sounds like it will have the potential to work well, as soon as they can figure out how much BMP to insert into the cage.

    Do all the research you can and then talk with your surgeon and ask him lots of questions. He may have performed many successful surgeries using this off-label.
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