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NumbskullNNumbskull Posts: 1,526
edited 06/11/2012 - 8:36 AM in Pain Medications
How quickly does neurontin start to work? I just got prescribed it today, and am just wondering when I can expect to start feeling the results. Thanks!!
APROUD CANADIANveteranButNOTa doctor, my thoughts are my own


  • Are you gradually increasing the amount? How much will you end up taking?
  • My pcp started me at 300 mg, 3 x a day, and then she said we could increase it after if needed. I've read the responses to the other thread made after mine, and saw that it's supposed to be increased slowly, does 900 mg a day constitute slowly? It seems to be a considerable lower dosage compared to the amount other people are taking.
    Due to timing, I'm only able to take 2 today anyways, and I'm off work tomorrow, due to having my nerve block, so I was going to go ahead with the 3, but I'm definitely going to be asking my pm doc his opinion.
    What I was wondering though, does it start to work immediately, or do you only notice the effects once it's built up in your system, and if so, how long does that take. I think my answer is found in the other thread, that it has to build up? I'm looking forward to noticing the effects, I just want some relief!!! But, who here doesn't... lol Thanks for replying Gwennie!!
    APROUD CANADIANveteranButNOTa doctor, my thoughts are my own
  • when I started, my doc started 300mg a day for 1 wk, then twice a day for 1 week then 3x's a day. I felt like a zombie on it. I slept all the time. I would try to force myself to stay awake but I couldn't do it. It was worse when I would try to read something like the newspaper or computer. I would fall asleep while reading. The benefit for me was minimal. I stopped taking it and started lyrica which made me gain weight and the benefit was also minimal. My legs still hurt so I decided it wasn't worth it for me.
  • It took a few days to build up enough in my system to make a remarkable difference.


    PS I hope it helps you out as much as it does me!
  • I take the UK form of neurontin, gabapentin and take 1200/day. I don't think it made me angry, but the pain made me angry so it's hard to say! It definitely works, for me anyway.

    Bye, Val
  • I took 300mg at bedtime only, as it made me feel so sleepy, and it stopped my nerve pain at night, and help me sleep. Right now I am going off it, and I am down to 200mg at bedtime, and a low dose did wonders for me, and I had a severe compression at L5 S1, and had surgery in Jan. 09, and it was great. Really helped me sleep and stop the nerve burn. I know most people take much more. My Dr. was surprised that such a low dose helped!! Only my experience! Plus, it helped me right away. sweetpotatoe57
  • I started out taking the 400mg capsules 2x a day and gradually increased.. and even had the 100 mg capsules. Now I just take the 300mg capsules. I was increased after much time to 3600mg a day and started having some adverse reactions when I went from 3000mg a day to the 3600mg. (strange)
    remember everyone is different..
    I now take 1800mg a day. that's my happy medium.
    It started working if I remember that far back shortly after starting.
    Most get a bit sleepy from neurontin.. but not me, I wish it did make me a tad sleepy I could use a helper for a good night sleep.
    It helps me so very much for the nerve pain I have in legs and my arm.. But the pain in my neck and back it does nothing for..
    Now that's just me. my experience
    Hugs to all...Patsy
  • Hi Kelly,

    My 15 year old son started Neurontin about 2 weeks ago and it is working wonders for his Trigeminal Neuralgia.

    He started out with 300mg three times a day and he noticed nerve pain relief rather quickly. It took a good week for this to build up in his system and he can adjust his dose up to 1800mg, if needed. He hasn't had any nerve pain for almost 6 days now, which is awesome. He was in extreme pain and the Neurontin has knocked it out for him. This did affect his moods and concentration at first, but he is now adjusting. When he first started taking this, he would get drowsy and this is a very common side effect.

    I hope you find great relief with the Neurontin. It has been a wonder drug for my son.

    Best wishes to you,

  • I am so glad to hear that your son is doing so much better, that's fantastic!!! You know, I just starting taking it yesterday, have taken 4 so far, and I do feel better. Not sure if it's because the weather changed, warm, sunny and dry after a cold damp and rainy week, if it is the med working or if it's all in my head because I want it to work so badly!! Whatever it is, I don't care, as long as it keeps up!!
    I asked my pm about it today (well, I had to tell him anyways, as it's a new med) and he said he would rather have me on Lyrica or Cymbalta, but to try the neurontin first is okay. It's weird, as he doesn't want to take over my prescriptions, but he seemed a little put off when I told him that my pcp gave me neurontin. Understandable, because we've been trying anaesthetic nerve blocks, which aren't working, but he said if I start trying new drugs when he's starting new treatments, we won't know if his treatments are working, or if it's the meds. Anyways I'm waiting to hear when I'll be getting the medial facet branch block done. Hopefully, between the two, it will work.
    I also asked him that while waiting for the branch block, as it could be a month or so, if we could move on to treatment of my leg (he wanted to start with one thing at a time). He seems to think, that along with the problem that all the muscle and tendons are fused together in my thigh, and the sciatic pain that radiates down into my leg, and the nerve pain and numbness I feel in my foot, that I have fibromyalgia. But then he said he doesn't like to be the one to diagnose things. So what am I to do? I guess go back to my pcp and tell her that's what he thinks. This going back and forth is driving me insane. Especially when I have to bring ideas up to my pcp, she has been great sending me for tests and seeing specialists, but it's all been at my request or suggestion. Who's the doctor here? Even the neurontin, the amitriptyline (I don't take that anymore) and the mulitude of NSAIDs I've tried have all been because I've asked her about them, or because she's mentioned them at one point, and then never did anything about it. Very frustrating. She did refer me for more MRIs, one of my brain, and finally of my lumbar region (she's been saying she would for months now) because of symptoms I have that MS patients have, and my sister has MS. My pm said that's a good thing to do as well. I really don't think I have MS, but it's good to rule it out anyways. The fibro to me seems more probable.
    Anways, I've got way off track of my original subject, does that mean I hijacked my own post? LOL
    Hope everyone is doing as well as they can be, warm wishes and peace to all.
    APROUD CANADIANveteranButNOTa doctor, my thoughts are my own
  • Hi Kelly,

    Thanks so much for your kind words for Zach. He's doing great!

    Just wanted to check in with you and see how the Neurontin is working? I hope it is helping you.

    Going back and forth between physicians is a royal pain in the butt. And yes, I guess telling your PCP the information would be your best bet right now.

    Please let us know how everything progresses with you. Whatever needs to be done to get your pain to a tolerable level will be worth the hassels right now.

    Take good care and hope you have an excellent weekend.

    Hugs to you,

    Tammy :)
  • That really is great that it's working so well for Zach, Tammy. It's such a sin to see someone so young to be suffering from the pain we do at our age, which is still too young!! I don't wish it on anyone of any age.
    Well, I think it's working for me, too!! The pain levels have subsided, last night and today is elevated due to being rainy, cold and damp out, but still, not as bad!!! I'll take it!!!
    It's also helping me so much with sleep!!! The past few months, I've been going on 3 hours of sleep, broken, on average. Even zopiclone wasn't helping anymore!! Since last week, I've taken naps, and still slept for about 6 hours at night!!! That is such a relief in itself!! Yes, it does make me drowsy, but I'll take that, too, over being a zombie from lack of sleep and beng in brutal pain!!
    Hope everyone out there is doing as good as they can be, and have enjoyed at east a part of their weekend and had something to smile about!!
    APROUD CANADIANveteranButNOTa doctor, my thoughts are my own
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