I know that many of us who are on opioid pain medications suffer from constipation. i just wanted to share what has been a miracle for me. I take Magnesium which is supposed to help with muscle cramping. I guess I never really put 2 and 2 together and realized that this is what Milk of Magnesia is derived from. I never have a problem with constipation and have been on the Magnesium for quite some time. I was wondering why I don't have a problem with constipation when I am on such high doses of Oxycontin and percocet but ever really gave it a whole lot of thought. Last week, I ran out of my Magnesium and kept forgetting to pick some up. I went days without it and then starting noticing that I was extremely constipated which hasn't happened to me since after my surgery. I still hadn't put it together that it was the Magnesium keeping me regular and went a few more days without it...and without a BM. LOL! I went out and picked up some Magnesium and started taking it again that night, and by the next morning, all was well again. Obviously, before starting any new medication, even if it is OTC, you should check with you doctor, but I just thought I'd share what works wonders for me.