I don't know how many people on this forum have had experience with genetic testing to see what medications they can tolerate. In a separate post, I had shared that my daughter is struggling with an excruciatingly painful neurological disease called RSD - Reflex Sympathetic Dystrophy. The pain she feels in her leg is the magnitude of having an amputation, over and over and over again. She has spent so many days and nights over the past three years crying, moaning, and even screaming in pain. It makes my back pain seem utterly trivial.
During the course of her 3-year journey now (and counting, because there is no cure for this disease), she has tried many treatment options. Interestingly, Physical Therapy is the golden treatment. It surpasses any medication available in terms of resolving her pain, and she has taken Morphine, Dilaudid, Tramadol, and Motrin. The latter two are the only things she takes today for break-through pain. She has also tried Amitriptyline, Lyrica, and Cymbalta, in an attempt to manage her neuropathic pain -- all of which caused horrific side effects for her.
I'm sorry for the poor intro because my post was intended to elaborate on a genetic test that is available to almost anyone who is struggling with medication. It is called "Cytochrome P450" or "CYP". Below is a link to a Mayo Clinic overview. http://www.mayoclinic.com/health/cyp450-test/MY00135
Please note that although the description mentions antidepressants, the test also provides very helpful information on a wide variety of pain medications as well. This is why I wanted to share the information on this forum. This test was tremendously helpful to our daughter's doctor, so I'm hoping it help some of you focus in on the medications that can really help you, and also save you a lot of time and agony by avoiding medicines that your body cannot metabolize.
I am not qualified to describe the test in detail. I would highly recommend that you talk to your doctor about this. I believe that even your PCP can order it, and I believe that it is covered by most insurance plans. Please check, because I believe that it can be rather expensive.
Best wishes to all!