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Medications for Insomnia or Anxiety Linked to 36% Increase in Mortality Risk

happyHBmomhhappyHBmom Posts: 2,070
edited 06/11/2012 - 8:47 AM in Pain Medications
From Medscape
Odds of mortality were 3.22 times higher for participants reporting anxiolytic or hypnotic drug use in the past month vs those who did not report use of anxiolytic or hypnotic drugs in the past month (95% confidence interval [CI], 2.70 - 3.84). This odds ratio (OR) was still significant but was attenuated to 1.36 (95% CI, 1.09 - 1.70), after adjustment for confounding sociodemographic, lifestyle, depression, and other health factors.

Limitations of this study include evaluation of sedative drug use using a dichotomous, yes-or-no question; failure to control for the presence of anxiety disorders in the prediction model of mortality; and reliance on self-report, creating the potential for biases regarding context, primacy and recency effects, suggestibility, and social desirability.
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