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Any research references for allograft vs autograft?

BuelaBBuela Posts: 67
edited 06/11/2012 - 8:58 AM in Back Surgery and Neck Surgery
I have a two-level ACDF scheduled 1/3/12. My doctor has given me the choice between allograft and autograft - he's explained the difference, explained the risks of each, but left it to me. Everything I find online about it is just personal experience and opinion -- and even when it's a doctor's opinion (even my own doctor's opinion), I would really prefer to also see research to back it up.

I know that autograft means another site to heal that could be more painful than my primary surgical site, and could carry with it some additional complications (nerve or muscle damage, infection, etc.). But I also know that allograft can reduce the chance of (or pace of) fusion.

I'm really hoping that someone can link me to some real studies on this topic.



  • Look up failure rates on multi-level fusions, using allograft and autograft. You should see the risk of failure to fuse go up as the levels go up. Also look at bone rejection, and their are some small risk of getting bone cancer from cadaver. I myself was told I would fuse(heal) faster with my bone, but would be more painful from the start. So I opted for the faster healing, sense my ultimate goal was to return back to my career as soon as possible. One other thing be sure you check the sources of whom did the study and the number of patients in it and how long they were followed.
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