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Compazine side effects

I was prescribed compazine for the nausea that accompanies my norco while working. I have just suffered with the nausea for nearly 2 years. Sometimes I get nausea sometimes I dont. Usually I do. It depends if I try to focus on things or move around a lot. Anyway... to those who have taken it... Does it cause a lot of drowsiness? I am going to try to take it tonight to see if it would be ok to take at work. I am hoping so.

I KNOW everyone reacts differently, just wondering what side effects you had.


ACDF C4-5 June 23rd, 2011

Another surgery in the near future. I am 26 years old.

Current Meds- Norco 7.5/325, Cymbalta 60mg, Gabapentin, Adderall 20mg


  • May I ask how long you have been on the Norco?

    The reason I ask is that I was on Percocet for quite a few years and then all of a sudden developed terrible nausea and stomach issues. After trying a few different nausea meds...we figured out it was the Acetaminophen in the Percocet and that my stomach just decided it had had enough!! LOL

    Literally within a week of switching to OxyIR which is the same opiate (Oxycodone) but without Acetaminophen added in...I felt great and haven't had a single issue since and am not on any "side effect" medications..

    So, if you've been on the Norco for a bit...it may be worth trying to switch to another pain medication to see if this helps..
  • It is worse now that it was previously. My next PM appt is in January. I only take 3-4 per day so its not that much apap, but it has been a while. I know they don't make hydrocodone without the acetaminophen, and oxycodone is worse with the nausea. Not sure what I would be prescribed if I cant take hydrocodone, oxycodone, tramadol and tylenol3. I don't really want to go to a stronger med either. Hydrocodone makes me the less sick of those meds.
    ACDF C4-5 June 23rd, 2011

    Another surgery in the near future. I am 26 years old.

    Current Meds- Norco 7.5/325, Cymbalta 60mg, Gabapentin, Adderall 20mg
  • Hi Donnabe, I also have severe nausea and vomiting with Codiene, hydrocodone, Oxycodone so my doctor changed me to Nucynta which is supposed to be better at preventing nausea and it works. I have been on since Feb. and not had one bout of nausea or vomiting due to meds. It comes in 50mg and 75mg. I started out at one 50mg every 4 hrs but now take two 50 mg. 3 times daily as needed. Not sure if this would be an option for you. It is very expensive and my insurance will ony cover 6 per day. If I had to pay instead of insurance it wouldcost me over 900.00 a month which is just ridiculous. Well, I hope you can find some relief from your issues and still have good control over your pain.

  • nucynta er also comes in 100mg, i have been taking for a month now, seems to help.
  • Is that a breakthrough med or a round the clock one?
    ACDF C4-5 June 23rd, 2011

    Another surgery in the near future. I am 26 years old.

    Current Meds- Norco 7.5/325, Cymbalta 60mg, Gabapentin, Adderall 20mg
  • I tolerate it well and it doesn't make me drowsy. I needed it when I was tapering off medication. You may want to try Vicoprofen, it's hydrocodone with ibuprofen. I couldn't take the hydrocodone with tylenol because the tylenol irritated my stomach.
  • avonldyaavonldy Posts: 61
    edited 12/15/2012 - 7:46 AM
    My PM switched me from Norco to low dose (15mg 2 times a day) low release morphine. I have had no side effects at all and I never wake up at night in pain. My PM explained that this was a very small dose that was better with chronic pain then Norco.

    I was worried at first because morphine seems so "hard core" but we can fine tune the dosage to meet my needs without any problems.
    I have Ankolysing Spondylits, Ulcerative Colitis, DDD and a bit of OA to make things fun. Most of my problems are due to inflation of many joints, tendons and ligaments. I see a GP, a Rheumatologest, an orthopedic Dr and a wonderful PM.
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