Grateful for all of you. I had a huge surgery May 15...poaterior cervical laminoplasty 4-level. IV pump in hospital produced no allergy but after two weeks at home I developed a rash on chest from Percoset but never any anaphylaxis. Itched from all of the others, got flushed, badly flushed with one called Oxymorphone, and even to Tylenol III. I had little red bumps at the tip of my tongue to most of them as well. Today tried Tramadol and my mouth got red and white bumps and flushed chest and nose and itch. Klonopin helps with muscles and I take Tylenol. Lyrica was mentioned to me and Neurontin. Any ideas would be greatly appreciated!!! I do take 55 mg of Norytriptylene for depression/anxiety and migraine. It's a great drug but not a pain killer. I am thinking about acupuncture but concerned about doing it so close to surgery. Hugs to all.