Diagnosed with ankylosing spondylities May of 2005. Started treatment with a variety of narcotics, including hydrocodone, Fentanyl patches, Fentalgesic, long acting morphine, and immediate release morphine. Every single one of them goofed my head. March 2012, taking 105 mg fast-acting morphine daily, and was pretty much useless.
Decided to kick daily narcotics, and I did. With the help of anti-inflammatory drug meloxicam, was able to reduce narcotic usage to one 10mg hydrocodone every two weeks. Then the meloxicam tore my gut up and had to discontinue it and other NSAIDS as well.
Tried tinzanidine, muscle relaxant; helped some, but was in so much pain I finally gave in and returned to the pain clinic, told them I needed something every day.
Doc put me on Butrans 10 mcg.hr patch. Helped, but not enough. Upped it to 20 mcg/hr.
I have absolutely NO head goofiness. NONE.
The patch relieves the VAST majority of the pain. I have a script for hydrocodone 10/325 for breakthrough, but I don't need that every day.
If I had Butrans back when, I wouldn't have had to take early retirement. This OUGHT to be promoted more by the insurance companies and other agencies that are slammed by the cost of people being stunned by their necessary meds.