This topic comes up several times a month.
I am posting some facts that come straight from Wikipedia and then I will give you my personal opinions since I have used both in the past.Pregablin (Lyrica)
is an anticonvulsant
drug used for neuropathic pain
and as an adjunct therapy for partial seizures. It has also been used to treat epilepsy, post-herpetic neuralgia, diabetic peripheral neuropathy and fibromyalgia
Pregabalin appears to be as effective as gabapentin for neuropathic pain; however costs more.Adverse drug reactions
associated with the use of pregabalin include
- blurred vision
- increased appetite and subsequent weight gain
- vivid dreams
- changes in libido (increase or decrease)
- attention changes
- abnormal coordination
- memory impairment
- dry mouth
- constipation, vomiting and flatulence
- erectile dysfunction
- peripheral oedema,
- abnormal walking
- increased creatine kinase level.
was originally developed to treat epilepsy
, and currently is also used to relieve neuropathic pain.
It is also commonly prescribed by doctors for many off-label treatments, such as restless leg syndrome, insomnia, and bipolar disorder. Adverse drug reactions
using Gabapentin include:
- weight gain
- and peripheral edema (swelling of extremities)
I started with Lyrica 75mg 2x day. For several weeks it helped with my nerve pain. My doctor then increased that to 150mg 2x day. A few days later, I noticed that from my knees down I was swollen. My foot ballooned up and I had
what some describe as sausage toes! I could fall asleep in the middle of a conversation. We contacted my dcotor and he had me drop back to 75 2x and then cut if out completely.
We then switched to Neurontin, 600 mg a day to start with, then 1200, 1800 and for me max out at 2400mg a day.
It did help very much with my nerve pains, but I had the typical weight gain (about 20lb) and frequently being drowsy/
I also felt that my short term memory was out the window. Before taking this, I admit as a man, I have selective hearing ( as my wife describes it ) , my short term memory was down the tubes but my long term is perfect. Now, I am lucky if I can remember what I did 30 minutes ago. I've talked this over with my doctor and we are not sure if it is the Neurontin, or perhaps the combination of all the medications I am on. Currently, I am on a downside for Neurontin. From the 1800mg a day I went to 1200, and now I am on 900mg a dayWhich is better for never pain?
I think that depends on the individual. For me, Neurontin wins hands down.