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Lyrica, Zoloft & Cymbalta

dkinyon31ddkinyon31 Posts: 3
edited 09/05/2014 - 12:31 PM in Chronic Pain
I had back surgery in 2002 to stabilize the low back and clean up the bottom 3 herniated disc. I now have 2 rods and 6 screws in my low back. The ongoing issue though is the bilateral neuropathy of the lower extremities coupled with a foot drop of the right foot. I have been on hydrocodiene and OxyContin but stopped due to the addictive nature of those drugs. My PM doctor put me on Lyrica which has helped some. Next my own doctor added Zoloft for the depression issues, which has helped some. Recently I ask and was allowed to try Cymbalta along with the above meds, but checking the drug interactions I found that there is an issue between Zoloft and Cymbalta. I seem to feel better though taking all 3 together though. I take 75mg, 1 AM & 1 PM of Lryica, 1 100mg of Zoloft of AM, and 1 60mg of Cymbalta in the evening.
My question is has anyone else had good results, or bad results taking these 3 medicines together? I am concerned mainly about the Zoloft and Cymbalta interaction.
Thanks for any help with this question!


  • mcjimjammmcjimjam Posts: 307
    edited 09/05/2014 - 4:15 PM
    I have taken those three medicines, although not all at once. If your doc is okay with the combination, it is probably fine. If it is working for you, that's fantastic and probably worth the tiny risk of the combination. JMO.
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