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Factor Five Leiden and needing surgery again!

I have posted here lots of times and am struggling with a decision to have a second microdiscetomy. I need it for a herniation at L3-4 and this is a repeat from 2 1/2 years ago.
After that surgery I developed a DVT a week later and found out that I have both FVL and protein s deficit. Has anyone else had back surgery with these issues and if so did you have difficulty with clots? I am very concerned to have another complication but I am at the end of my rope with the horrible leg pain! I have tried 2 epidurals which haven't worked so my next step is surgery. Anybody out there that can contribute would be appreciated.


  • nutcase007nnutcase007 United StatesPosts: 129
    edited 01/30/2016 - 10:58 AM
    I have Factor Five Leiden, Protein S deficiency and ITP. I'm on warfarin because I had two DVTs. I've had two cervical fusions without any issues. If you don't have a hematologist, your should get to know one.
  • Liz53Liz53 MissouriPosts: 142
    I have a hematologist but my concern is he has a different opinion from my surgeon. My surgeon wants me to wait 5 days after the surgery before he starts an anticoagulant. The hematologist is checking around to see what others do in similar situations. Do you remember how long after your procedure before starting anticoagulants? Just your opinion not that this is something I will take as advice. Very concerning to get any more clots! I know this is common enough that there have to be others out there in a similar situation. I would like to hear anyone else's experience with this.
  • hvillshhvills Suzhou, ChinaPosts: 724
    I take a daily dosage of time released Aspirin for my heart condition. My surgeon took me off it a week before surgery and substituted some kind of a daily injection (that bruised my skin quite badly) otherwise he said he would not be able to control the bleeding during surgery. Once the surgery was over I went back on the daily dosage of Aspirin the next day.
    Harry - 63 year old male...
    PLIF L4-L5-S1 due to disc degeneration... May 23, 2013
    PLIF L5-S1 due to failed fusion and broken screw... Jan 19, 2015
    Microdiscectomy, decompression L3-L4 due to herniated disc... Jan 19, 2015
  • nutcase007nnutcase007 United StatesPosts: 129
    I'm on Warfarin. If you are on a different anticoagulant, the "bridge therapy" will be different. If I remember correctly, they had me stop the Warfarin five days before surgery and bridge using Lovenox (expensive). I forget if they had me use the Lovenox right up to surgery and restart right after surgery, but if there was a break, it was very small period of time. They then had me restart the Warfarin shortly after surgery, since there is a "ramp up" time with Warfarin. I had to stay on the Lovenox until the target INR level.

    If you are on a different anticoagulant, the process will be different. Make sure your surgeon and hematologist are on the same page before surgery! Anticoagulants are a pain, but better than having DVTs.
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