
Fig 1: Healthy Microtome Section
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The vertebral disc in the spine is an interesting and unique structure. Its primary purpose is to act as a shock absorber between adjacent vertebrae. Spinal discs also act as ligaments that hold the vertebrae of the spine together and as cartilaginous joints that allow for slight mobility in the spine. There are a total of twenty-three vertebral discs in the spinal column.
The outer portion of the disc (annulus fibrosus) is the tough circular exterior composed of concentric sheets of collagen fibers (lamellae) that surround the inner core.
The inner core (nucleus pulposus) contains a loose network of fibers suspended in a mucoprotein gel.
The annular fibers hydraulically seal the gelatinous nucleus and evenly distribute pressure and force imposed on the structure.
The outer portion and inner core of the spinal disc fit together like two concentric cylinders and are interconnected by cartilagenous end-plates.
At birth, eighty percent of the disc is composed of water. In order for the disc to function properly, it must be well hydrated. The nucleus pulposus is the major carrier of the body’s axial load and relies on its water-based contents to maintain strength and pliability.
The spinal disc itself has very few nerve endings and no blood supply. Without a blood supply the disc does not have a way to repair itself, and pain created by the damaged disc can last for years. In general, as we age there are less inflammatory proteins in the disc space and discogenic pain rarely occurs after 6o years of age.