The main advantage of the drug over traditional NSAID’s is that it inhibits the specific enzyme associated with inflammation, fever and pain without disrupting the enzyme associated with the integrity of the stomach lining and maintenance of platelet and kidney functions.
Hence, COX-2 inhibitors can be used in treating chronic pain-related inflammation with a minimal risk of gastrointestinal complications. COX-2 inhibitors do have their own unique potential risks and complications and are available only be prescription.
Celebrex