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Lyrica and Swelling/Water Retention

AnonymousUserAAnonymousUser Posts: 49,578
edited 06/11/2012 - 7:23 AM in Fibromyalgia
I have been taking 25mg of lyrica for 1 week and are already having a problem with a feeling of inflammation/swelling. VERY achy in extremeties.

Has anyone had a doc. tell them what to do about this issue other than stopping med?

I just read somewhere that dieretics aren't helpful with this issue.


  • :) 25mg is such a small amount of medication. i take 300mg every evening and have noticed a weight gain. you should talk to your doctor if you are having such a severe reaction with that small amount. i want to welcome you to the forum as well! good luck and keep us posted. Jenny :)
  • I take 150 mgs. 3 times a day. It is a wonder drug for my sciatica.(not my other pain though)Of course I gained quite a few MORE lbs.*sigh* But weight gain is better than the pain.
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  • I gained 15 pounds from takin lyrica 25 mg...In 1 month Of course i told my Doctor about it he took me off them weightgain is a NO NO to us spineys the heavier we get it affects our backpain the most...Good Luck in finding the right meds... :)
  • Ok i am swelling up so much, i feel huge. my legs hurt they are so tight, the doctor says it my medication, but because i take so much hes uncertain wgich one it is. So i have to go back to see my PM doctor as he was the one who prescibed them. I am taking a water tablet, for the past 3 days now and today i can see my legs starting to go down.

    Angie :(
  • I had to stop my Lyrica, it slowed down my gut too much unfortunately (gastroparesis) so its back to the drawing board for me. :(

    Hope you can find a compromise with your PM Angie!

    We are tired of hurting I know. :(

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  • I was up to 600mg of lyrica and gained alot of weight. I started stationary bicycle 30 minutes a day and also lasix 20mg once a day. My leg and ankle swelling went down. I'm not sure what made the swelling go down. I'm now down to 300mg a day and still take lasix and bike and the swelling has stayed down. I agree with above and you should call and review this med with your Dr. Take care Charry
    DDD of lumbar spine with sciatica to left hip,leg and foot. L4-L5 posterior disc bulge with prominent facets, L5-S1 prominent facets with a posterior osteocartilaginous bar. Mild bilateral foraminal narrowing c-spine c4-c7 RN
  • Boy, that's a big subject for me right now. I feel that maybe my Lyrica is a problem for my weight gain to some degree but I also am Hypothyroid. I wasn't happy the last time I went to the doctor I was almost 160lbs. I hadn't been in almost a year when I weighed 140lbs. What's up with that. I'm really going to talk to him the next time I'm in there in July about it. I had to see his practioner which I didn't care for. I do get out and walk my dogs, which is about the extent of my exercise right now. I know I should be eatting better than I have been lately. So, I'm pretty sure my weight gain is a combitination of it all. It's definately frustrating I know that. I used to be so slender now I feel frumpy.
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