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Cadillac of Pain Meds? Opana ER

kcrozkkcroz Posts: 33
edited 06/11/2012 - 8:23 AM in Pain Medications
I am taking 40 mg of Opana ER three times a day. It is not working. I am waiting for a permanent cervical SCS. My PM says this is the Cadillac of pain medication and there is nothing else he can prescribe. I have been on this dosage for several months. When I started taking it, I was very nauseous but after several weeks my body adjusted. Before I was taking Oxycontin. My question - has anyone switched back to Oxycontin from Opana ER? This is why I need the SCS! I think everyone's tolerance builds and it gets to a point where nothing works anymore. I have read prior posts regarding the bio availability of Opana ER. I just need some relief.



  • I use to use opana and yes I did switch back to Oxicotin. You may get some reliefe from switching back ot and oxicodone. Opana is a ER version of diluadid and I built a tolerance to opana due to the amount of surgeries I have and dilaudid is what I use for IV meds in hospital.

    Would like to know how your SCS goes would love to get one after I heal from my next surgery.

  • i've said it a million times here before and I'll say it again.. Opana ER SUCKS. It's bioavailability is only 10%, which means you only get 4mgs of that 40mgs into your bloodstream. Oxycontin is about 90%, so you get about 36mgs of a 40mg pill, which is why it works SO much better. Your doctor is misinformed.
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  • btw opana is NOT a version of dilaudid. Dilaudid is hydromorphone, while Opana ER is Oxymorphone. ~
  • My PM switched me to 80 mg Oxycontin three times a day. I can pick it up on the 6th. If I am understanding JVM correctly - even though he prescribed double the mg's of Oxycontin. My body should be getting 210 mg of pain relief instead of 12 mg daily. That is a BIG difference. As I said before, when I started taking the Opana ER I was nauseous for days. I thought it was because it was stronger. Now I am wondering if it was withdrawal from Oxycontin. Guess I will know in a few days. My PM also said out of all his patients, I am on the strongest dosage of pain meds. Does anyone else take this much pain medication?

  • the Opana IS 3 or 4 times stronger, by milligram, so that 12 would be 48 versus your 210, big difference still right? If you havent had 80's yet, ask your doctor, but I'd start at 2 a day, one morning, one night, for a week, before going to three, that's a hefty dose! It can cause nausea too; just plan on it, keep some sprite or other light soda around, prepare to lay down and watch a movie or something, and after a bit the nausea will pass. You are on a high dose, and yes other people here do take that much, but I am guessing you have had, or are probably GOING to have surgery sometime in the future? Just keep a log of your activities. 3 of those a day and I'd be smiling, happy, and drooling.(with MY pain) Let us know how the switch works for you! I am SUCH a 'Opana sucks' kind of guy that I'd love to hear a success story from someone. And since you were on oxy 40s before, please, try two a day, trust me, it'll make things a whole lot easier and you might be able to just hang onto the third one in case.. if you doctor says so at least! Good luck!

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  • I have been cruising around this web site for months and never really had much to say or offer so I have never written before. But I just had to say that I always read the emails from JWM to be helpful and very interesting. My PM used to have me on Opana IR for breakthrough pain and I also thought it was awful and when I read about the bioavailability on this site I understood why and had them switch me back to oxycodone. Also for the writer wondering if anyone takes as much medication as she does well I wear 200 mg in patches of Fentanyl and take 4 15 mg oxycodone for BT as well as other meds and I function really well working as a nurse. It takes a lot to knock me out after 4 back surgeries with all the hardware. Anyway,Thanks JWM. You are pretty smart.
  • I have been behind the scenes reading for sometime now, but finally decided to join in order to post. kcroz, I am glad to see that your MD increased your dose, because despite the claim that Opana ER is the cadiallac, they still need tune ups. As with all narcotics it is possible to build a tolerance to the medication, therefore requiring an increase in dosage.

    As to the concern about others being on high doses, Allow me to reassure you that it is possible. I am on Fentanal 200mcg every 48hrs, Opana 80 Three times a day, and I utilize oxycodone 30mg 1-2tabs every 4hrs as needed for breakthrough pain, along with baclofen 10mg TID. and yes I am still fully functional, working full-time.

    I have been on long-acting pain meds for 4yrs. I have a chronic nerualgia in my right lower abdomen from a surgical wound as well as a T7-T8 disc herniation with spinal cord compression, distortion, stenosis and now swelling. Which is scheduled for repair 10/16.
  • i hope they find the right adjustment and the right med for you!! everyone should be able to live a normal life.

    for the others that have joined WELCOME. you came to the right spot that is for sure.

    just remember we are not medical professionals and can only give you our own personal experiences with these things.
    any reaction or such to a med please contact your dr or pharmacy.

    please can some of you send your PM docs to my area??? man oh man. i was lucky to even get 10mg of oxy 2x's a day. i told the dr it did not work. he did not up it.
    so we went to morphine that was a no go and he did not up it.
    then we went to the patches well we did start at 12.5 then he upped it to 25. HELLOOO NOT WORKING.
    so he did not up that one.
    then said the last thing was methadone. i was on 5 mg 2xs a day and well it worked for awhile but lost its effect as my back issues needed to be fixed. he was stuck on 4 meds and that was it. :O :O :/ :/ :B :B
    mind you he would not BUDGE on breakthrough meds. said if i wanted that i would have to cancel my contract with him and get them from my pcp. OK FINE...

    ya think that pain managment would be a governement type thing if ya know where i am coming from. all pain managment drs that treat long term pain should all be able to work with your correctly in treating your pain and give break through meds. i just don't get it.

    anyways sorry for my little rant. ;) ;) it just gets me i live with pain levels high most of the time and no one is around to help.
    and it really stinks when you have proof to back ya up.. ~X( X(

    GOOD LUCK HUN in your journey of getting the right med for you!!!

    terri >:D< >:D< >:D< O:) O:)
  • I'm wondering how kcroz is doing.. If I had to guess, probably better, but 3x80 oxycontin a day is a lot! I remember when I went from a few norco and 4 15mg oxy IR a day to 3x40mgs Oxy ER, wow, it threw me for a loop and really I was pale in the face for a week it was so strong. That's one of my other fears with these doctors who think Opana is so strong; its NOT, and going from 40mg Opana to 80mg Oxycontin is quite a leap in strength..

    I'm hoping kcroz is opiate tolerant, used to oxy, and doing well.(I didn't mention it before, in this post at least, but even 3x20mg oxycontin ER a day is stronger than the 3x40mg opana.. hence my slight concern..) Please post kcroz!

  • :) crazy5, hi and welcome to the forum! :H we are here to offer you support and answer what questions we can. JWM does have alot to say and is a smart guy. i like to read his posts too. good luck on your upcoming surgery. Jenny :)
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