So, I must admit I'm somewhat skeptical when people attribute all of their weight gain to a particular medication. But, I have to admit unequivocally that Lyrica causes weight gain. I've gained 8+ lbs. in 4 weeks (152 to 160lbs+). I can't possibly blame myself for more than 1/2 (a stretch) of that since while I am less active than usual I am still active and not eating much. So I'll take the extra pain as I taper off Lyrica- Not willing to put up with the weight gain. Evil drug since it does work well for my sciatica.