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POLL: Best extended release pain pill???

AnonymousUserAAnonymousUser Posts: 49,578
edited 06/11/2012 - 7:35 AM in Lower Back Pain
I am having great difficulty finding a good 24hour pain killer.... would love to have some input from all of you, so I can recomend one to my doctor. Please base your opinion of 2 main things

1)Pain relief

2)side effects (i.e. lethargy, drowsiness, joint aches..etc)

here is what I found so far:

Ultram ER(tramadol): No relief whatsoever with 400mg
(2 200mg pills)

Ryzolt ER(tramadol): Some MINOR releif but alot of
breakthrough pain (2 200mg pills)

Kadain: Not much pain relief, side effects were
horrible..i.e. out of breath, tired all day,
weight gain and joint pain (20mg/day)

OPANA : Have not tried yet, prescription sitting in cabinet
Afraid to take due to sides from kadain

Thanks for any imput!!!! would love to find one that allows me to stay active during the day (non lethargic) but also actually relieves pain..OXYMORON or not????


  • The only heavy pain med. that works for me is Perocet. Tramadol made me sick, in fact a lot of them do so I am a hard patient. First tried Cymbalta, I wanted to shoot my doctor, It made me really sick. I try not to take anything but have to take Soma for muscle spasms. I haven't taken Perocet in a few weeks and I'm trying to stay away from it because it's habit forming, yet it is the only thing that takes my pain away, yet I get sad on it. I can take a little unhappiness over vomiting. All other pain medicines just make me sick.

    Ifyou do find one you like please let us know and it's a great post, love to hear what people do to get some pain relief.

  • Hey Mavrick77. This is actually the first time I've posted something here but I think I have a good suggestion. Oxycontin may be your best bet for extended pain relief. It doesn't last for 24 hours, but it is a 12 time release drug.

    In February I was almost murdered when I was randomly attacked while hiking. I was stabbed 18 times and fell about 100 off a cliff. I broke my neck(c2-c3), fractured my skull, both my lungs collapsed. I suffered several other injuries but I don't want to make this post too long.

    I've been on Percocet for 6 months and have found it to work very well. I feel great when I'm on it but it only lasts 2-3 hours. A month ago I underwent anterior cervical fusion because my neck wasn't healing. Since then I've been prescribed Oxycontin and took it after I ran out of Percocet and it has worked very well for me. I've heard from so many people that Oxycontin has given them their lives back since they can live relatively pain free.

    Oxycontin can be very addictive, but I'd rather live with that stigma than live with pain. With the exception of minor itching, I haven't noticed any side effects. Everyone reacts differently. Hope this helps.
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  • thanks for your replies... I take norco 10mg's for breakthru pain at night and to help me sleep...however still looking for the magic one for the day time.

    To be honest I am a bit terrified of oxy's due to their highly addictive nature, thats why i started this quest with the tramadol...however it seems if you truly want any relief, you have to go with a strong narcotic.

    I wish I was as lucky as the previous poster and be able to go for weeks with out anything, however, my pain is bad enough that a 230lb guy start tearing up even with 2 norco 10's in me...I am just looking for every last option, before I even try a fusion, however at my age, that is a bad option (only 32)

    I am finding that one drug just leads to another.... due to the pain meds, I cant sleep at night...so I have to take a ambien to sleep....due to the pain meds its hard to have sex, so I have to take a viagra for that...christ I just wanna break this damn cycle.
  • there is no such thing there is a 12 hour pill i take the 80mg Oxycontin but i need to take breakthrough meds too after about 6 hours the pain starts to get unbearable 20mg oxynorm for breakthrough pain
  • Hi Maverick,

    I found that Vicodin (hydrocodone) works very well for me, I notice no side effects . Percocets also work well but I found thay made my skin itchy and it gets quite annoying to always be scratching.
    Oxycontin works REALLY well, but it can be highly addictive. For some its worth the risk of addiction to at least live a with the pain relief. If that was the only thing that worked for me I would take that risk, but thats me. It might take you a while to find what works for you, don't give up.
    Also, chronic pain can sap your sex drive. Its physically and mentally draining.
    Hope this helps.
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  • thanks for your reply lisa..I am currently on the norco 10's (vicodin 10mg)... they do work well, but my body is very used to them, I am up to 3 a day and not getting much relief

    Straker...if you look up Kadian ER, or Opana ER, Ultram ER, RYZOLT ER...thoose are ALL 12-24 HOUR extended release pain meds, they have not worked for me, too many sides,or too little pain relief.. but some seem to love them. so they do make them, but how effective they are I dont know. my vicodin only last bout 4 hours
  • I am taking Avinza, which is similar to MS-contin but in a 24 hour release tab. It works pretty well, and I have had no side effects.

    My PM is still trying to get the right mix, I'm currently taking 60mg of Avinza and 100mg of Tramadol during the day. I'm leaving for PM visit in the next few minutes, we'll be evaluating whether to increase the Avinza. I'd really like to eliminate the Tramadol except for PRN.
  • and as for as i know {i have looked in the BNF} the British national formulary we tend to define extended release medication in the 12 hour mode .but i understand that many of them dont last 12 hours thats why many take breakthrough medication {i do myself}
  • Jay - does the Avinza really last the 24?


    EDIT - after Straker posted;

    That is my understanding, I have been on MSContin for a couple of years. Gives me 9 to 11 hours of relief. I use the BT meds when the peak hits and when I need to fill in a gap.
  • Well, I find that Oxycontin works the best out of all the ER meds I tried, even Fentanyl patches. I know it says that it lasts 12 hours but for a lot of us it's more like 8. I take 80 mg's a day of Oxycontin and it's 1 40mg tablet twice daily. It doesn't make me drowsy and tired like 180mg's of MS Contin and 60mg immediate release morphine. I have no side effects with it either.

    I know that people think it's highly addictive, but as long as you take it as prescribed and only for pain, the chances of addiction is very slim. And I won't let anyone give me any slack about taking it; it's my business and prescribed by my doctor.

    Let us know if you decide to try your Opana. I'm curious to know how it works for you. Take care
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