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Anyone tried Methadone compared to oxycodone

davidmddavidm Posts: 32
edited 06/11/2012 - 8:58 AM in Pain Medications
Has anyone tried Methadone for pain? How is it? Compared to oxycodone?

I'm currently on Oxycodone 30mg 4x day and MS Contin 15mg 2x day

I know that everyone is different, just wondering how was your experience with Methadone?

If you were on methadone and oxycodone, which helped more?

Thanks for your help


  • I did beter with the oxycodone, once they had me try methadone and felt prety bad so i turned it down, But then again i never did well with the realy heavy stuff.

    I try to just manage with norco and valium when it gets real bad, valium is just a life saver to avoid er,
    Flexicore ADR 2004 resulting nerve damage l4l5 Fusion 2006 same level, 2009 hardware removal with lami !
    2012 scs implant ,
  • Methadone is a very , very good medication for treating both mechanical and neuropathic pain. The difference between methadone and oxycodone or any other opiate is that methadone has a very long half life. Where most opiates half life is much shorter, methadone's half life is around 36 hours, more or less. This means that half of the dose of methadone is still available in your body around 36 hours after your last dose. For this reason, methadone needs to be slowly titrate up or down in dose.
    Any time one goes on a new medication, you need to give your body time to adjust to the side effects of the medication, as well as time for at least one dose adjustment to see how well it will work or not work for you. The side effects usually lessen in about two weeks, but can return for a short time after a dosage increase so you should be aware of that as well.
    It is also one of the cheapest pain medications on the market today and one of the most effective.
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