I was researching information regarding BuTrans and came across this site. thank you all for the information I have read thus far. I was diagnosed with Spondylolisthesis at the ripe old age of 3 when I was in a car accident and further crushed my hips and landed in traction for several months. I was told I would never walk, but obviously too young to listen! through the years I have purchased many a new car for chiropractors and doctors alike! I have successfully avoided PM for 50 years through diet exercise and chiropractic health, but the last 2-3 years my mind and back are just plain worn out! So I have gone to "Plan B" in hopes of some sort of relief, I do not ever remember waking up without pain, nor sleeping more than 5-6 hrs as a result of my inability to lay down, sit, or stand for extended periods of time. So I finally gave in to try pain management. I just started Bu Trans and as of day 3 I'm not seeing much relief, but I understand it takes time, I guess the good news is I'm not seeing all those side effects either! I'm very grateful for finding this site, I've had pain for so long that is has always been normal to me, I'm grateful to have found what I hope is a great support and information site. Thank You.