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Cymbalta For chronic pain pros and cons

My Dr wants me to try cymbalta along with my Vicodin. Does anyone here use it for pain? What are the pros and cons? I've heard some pretty rough side effects and I don't want any weight gain.


  • SavageSavage United StatesPosts: 7,385
    ......PM doctor did try the cymbalta with me and I also have depression....so it was to be a win win.
    It seemed to benefit both pain relief and helped depression for a time...but then seemed to stop working altogether.

    For me, it was in addition to pain meds at that time.

    I did not gain weight.
    Honorary Spine-Health Moderator
    Please read my medical history at: Medical History

  • MikethepikeMMikethepike MIchiganPosts: 676
    more muscle tightness. Mainly around the neck. But he had me on 60 mg. twice daily
    So I was taken off it.
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  • patrain17ppatrain17 Ottawa area, CanadaPosts: 106
    My doctor suggested me to take Cymbalta to treat my pain, my temper and my frustration.

    I had a really short fuse at that time and had difficulty to control my emotions. I was always mad at something and would really give my wife an attitude. She had enough and talked to my doctor. I admitted to having such a problem and that's when he came up with the idea to put me on Cymbalta.

    I've been on it since. It really helped me with my temper and a bit with the pain. I tried to go off it a few months ago but the side effects were so bad I had to start taking it again. I am now at 30 mg a day and hope to find time this summer (I have 10 weeks off during the summer) to wean off it. I just wanna know if I can still function without the med.

    As for gaining weight, I did gain a bit but I just think it is the result of not being able to do as much activity as I used to before my surgeries. Not sure Cymbalta as anything to do with it.
  • I am an odd ball with anti-depressants when I tried it I woke up standing at my kitchen counter chopping up my meds on a cutting board and pouring Gatorade on them. I was so desperate for relief that I tried it again and my breathing and heart rate were way off.
    So far me never again and I wanted to have the great results others have had, but we all know each of us is so different when it comes to our reactions to meds.
    I hope it works for you and gives you everything you are wanting from it.
    Take care
  • EnglishGirlEEnglishGirl Posts: 1,825
    edited 05/02/2015 - 5:45 PM
    When I first started taking it I remember telling my doc that it didn't seem to do anything for my pain but it did improve my mood. I continued taking it. Doctors didn't want me to stop taking it, saying it was really hard to ween off & it will "Fry my brain" to try!!! I ended-up taking it for a couple of years (I know!!) I finally put my foot down & insisted I didn't want it anymore. My new (at the time) doc gave me a slow titration plan & it was easy-peesey to stop. Soooooo easy! We're all different though.

    No weight gain. When I stopped taking it it felt like someone had turned the lights on & I hadn't realized I was sitting in the dark! Very strange experience for me.

    I think it's worth giving anything (within reason!) a try. You never know. I stick with meds, after any dose adjustments, for a month or so unless I have health threatening side effects. A lot of meds make me sleepy for a couple of weeks at the beginning.
    Osteoarthritis & DDD.
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