My PM put me on these patches a few weeks ago - first the 25s and now the 50s. While I've used the 100s before (about 10 years ago) I don't recall any significant side effects and I've been on the patches long enough that I should have adjusted. However, this time I have trouble sleeping - I was up all night last night - I itch like I've been in poison ivy, and I am breaking out with bumps all over. I've used antihistamines, calamine lotion, aloe, and various anti-itch lotions but nothing seems to stop the itching. I've also been taking either tylenol PM or advil PM to try to help me sleep but neither seems to work for me. I appreciate any and all advice on dealing with these side effects, voodoo, chicken bones, tea leaves, etc. anything to stop itching and get some sleep!