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Can more than one nerve root be affected in a herniation? For Example, could an L5/S1 affect both the L5 nerve root and the S1 nerve root? Still waiting on an MRI, but I have had partial numbness on the outside of my foot that is moving across my toes, bottom of foot & up the back of my leg with some significant sciatica. Looking at the maps, it doesn't seem to line up right with the nerves.