Potential Risks and Complications of Prolotherapy

The injection technique involved in prolotherapy requires skill and care on the part of the physician. Training and experience are important.

Possible side effects may last a few days to a couple weeks and include:

  • Swelling
  • Intense pain and stiffness
  • Headache
  • Allergic reaction

Reports of more serious complications have been rare, but could include:

  • Spinal fluid leak
  • Permanent nerve damage or paralysis
  • Pneumothorax