Transforaminal lumbar interbody fusion (TLIF) is a common lower back surgical procedure that aims to eliminate motion in the treated spinal segment and allow the fusion of bone. The surgery is comparatively less invasive than other spine fusion surgeries and helps preserve vital ligaments and reduce the risk of neural injury.,,,,

While TLIF is considered a safe and effective method of achieving lumbar fusion, failure of bony fusion, migration of the cage, and misplacing of screws may occur in rare cases, providing incomplete symptom relief.

In This Article:

Success Rates of TLIF Spine Surgery

Studies indicate that most cases of TLIF show favorable results:

  • There may be a 60% to 70% improvement in pain after a TLIF spinal fusion surgery
  • Both open TLIF and minimally invasive TLIF have a high fusion rate of around 90%
  • More than 80% of patients undergoing TLIF spinal fusion surgery are satisfied with the surgical result

TLIF fusion rates are similar to the other approaches to spinal fusion, as seen at the 2-year mark after surgery. Patient satisfaction is nearly 95% 2 years following a TLIF surgery.

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Potential Risks and Complications for TLIF Back Surgery

The benefits of TLIF spinal surgery must be weighed against potential complications from the procedure. TLIF has an overall complication rate of about 8.7%. Potential risks and complications include, but are not limited to:

  • General anesthesia risks. When under general anesthesia, the patient may be using a breathing tube and a catheter. The anesthesia may have side effects that fade over time, such as dizziness, nausea and vomiting, or shivering. The use of associated devices poses additional risks, such as infection or sore throat.
  • Infection. As with any surgery, there is a risk of infection at the surgical site. Infection may be due to the use of medical tools and devices during surgery. During the hospital stay following the procedure, the patient is monitored for any signs of infection. Obesity, diabetes, and smoking are important risk factors for post-surgical infection.
  • Excessive blood loss. While patients can donate blood in advance of the surgery and can receive a blood transfusion during or after surgery, excessive blood loss is still an important risk to consider. For example, individuals who are taking blood-thinning medications may not be cleared for surgery because of the potential risk.
  • Nerve injury. Although TLIF is designed to reduce nerve irritation, like any spinal surgery, it is still possible that the nerves can be damaged during surgery. The risk arises from the process of accessing the spinal canal, decompressing nerve roots, removing disc material, placing the interbody devices, and/or pulling nerves aside.
  • Lack of a solid fusion. Also known as pseudoarthrosis, this risk is common in all spinal fusion surgeries. A failed fusion may be corrected with a second surgery.
  • Continued lower back pain. If the surgery fails, lower back pain may persist, or a new onset of lower back pain may develop. The risk of new back pain is generally greater in open TLIF than in minimally invasive TLIF.
  • Paraspinal iatrogenic injury. The paraspinal muscles (muscles surrounding the spine) are pulled aside during surgery. When these muscles are kept aside for a prolonged period of time, there is an increased risk of injury to these muscle groups. If injured, the paraspinal muscles may be a continued source of back pain regardless of whether or not the spinal fusion was successful.
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Additional medical complications from surgery can include pneumonia or circulatory problems, such as heart attack, stroke, or blood clots. Risks and complications may increase if the patient undergoing surgery is obese. Minimally invasive approaches to TLIF aim to reduce blood loss, hospital stay, and risk of injury associated with open spine surgery.

While serious complications are uncommon, there is no guarantee that spinal fusion will be completely successful after TLIF. It is important to review the patient’s symptoms and diagnostic study results with the surgeon to ensure that TLIF is the surgery of choice for the condition being treated.

Read more about Spine Fusion Risks and Complications

Dr. Ehsan Saadat is an orthopedic surgeon practicing with Saadat Spine at Cedars-Sinai Spine Center in Los Angeles, CA, where he is also the Director of Research. Dr. Saadat has been published in numerous peer-reviewed medical journals, and from 2015 to 2016 he was the Editor-in-Chief of The Orthopaedic Journal at Harvard Medical School.

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