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ana blood test

baffledbbaffled Posts: 375
edited 06/11/2012 - 8:34 AM in Neck Pain: Cervical
just received a copy of blood work done in June - It was the anti nuclear antibody test. It was positive/abnormal, with a ratio of 1:320 - which is moderate/high - and the pattern suggests Mixed Connective Tissue Disease.

All I have read is - not to jump to conclusions, it is only one indicator (a good indicator - but not always conclusive).

Was wondering if anyone has had blood work like this performed with some similar results and what that meant to your treatment plan.

I have tremedous pain from just above the jaw line to the bra line - no ROM from neck thru the shoulders. Have a moderate herniation of c56, lost of arthritis and bone spur complexes - have an appt with a new nuerosurgeon tomorrow.

Any guidance is appreciated.



  • Why exactly was test performed? The diagnoses the doctor used?

    You sound very much like me the past 8 months or so. I have the same symptoms and more. I think its best you wait to hear from your doctor to be honest hun. You could hear many people guess at the problem and it would just increase your fears and make you very nervous. Its best to remain calm and try not to worry. The doctor is the educated specialist and I am just living the experience and nobody is exactly the same. I wish you the very best :)
    2005-ACDF with Corpectomy at C3-C-5.
    2006-L4-L5 diskectomy.
    2009-Cervical laminectomy at C3.
    Steroid injections series x 4.
  • I hope your appt went well, and the dr was able to explain the results. What did he recommend?

  • I have never had that test done and don't know much about it. I should say to my knowledge, it hasn't been done. I am curious as to what the doctors suggest to you though. I take it was a specific test and not in a standard profile test? I have had the C-reactive protein test that came out high but I am curious what they say about this test.
  • The appt went well -He has me scheduled for new mri of cervical (last 1/08) and a new set of xrays with flextion and extension.

    He has me referred to a RA/Spine Doctor to further investigate the Positive ANA test. From my research - my test could mean something or a be a false positive. My symptoms (and my own diagnosis - lol) is perhaps a form of Lupus. But I think I will wait for the doc to do what he does best.

    He feeling is that i have a form of Myophiscal syndrome (spelling?) He was shocked after he examed my neck and back area that I am on zanaflex - it appears it is not doing anything to relax my muscles. Even the botox -2/09 didn't do anything to get the muscle to switch off. He is running the mri and xrays - to make certain that there is nothing in the spine itself creating my intense muscle issues.

    The ct scan i took for him (that the docs told me i had a moderate herniation at c56) - he said is just shadows to him - hence the mri.

    The good news is I feel like we are progressing forward and he hopes to get all this done in one day. Get the xrays, do the mri and meet with the new doc and him in one day - and he wishes to have this done by the end of the month. No more see you in 30 days after the test and so on.

    It is amazing what technology will do - the doc's will be able to see the films thru the computers that day and review them with me there! thank you all for your support

    the doc that ordered the ana test - was looking for Rhum. Arthritis or some explanation for the pain and muscle condition. Maybe this was a good hunch on his part.

  • Hey Patti.
    Good to hear you have progressed with the doctors and they are looking for the source of it. There is chronic and acute myofascial pain syndrome. If that is what he/she was referring to. It is a fancy way to say you have trigger points. Although chronic trigger points can do more damage to the sheath and cause other issues. I have them chronic and while we do trigger point injection therapy they always reappear. While I like you take muscle relaxer as of late they aren't working again either. Those trigger points can get so large they actually can make you skin painful as well. My suspicion is since you have a bad disc they are coming from that. But then I am no doctor.

    I like the idea the doctor will be looking at the test results in the same day. So you won't have to sit back and wonder what in the world do they say and stress over it. Sounds like he/she has a good plan of action. Keep us posted how it goes.
  • I had positive ANA before but it was long ago and I don't remember what the reading was. All I know is that it was speckled. Other blood work that popped up positive was anti cardiolipid antibodies, false positive VDRL and I was told I had vasculitis of some sort. I haven't seen a rheumy doc in over 3 years since my back problems started. I was however diagnosed with lupus initially but then another doctor changed it to (UCTD) undifferentiated connective tissue disease because I didn't have enough markers for specific lupus. He said it manifested itself as lupus like and so they treat it as such.

    Sometimes it takes years for the disease to fully come out and you will fill vials after vials of blood for labs in the process. I'm pretty sure it played a role in my back problems because of the severity of DDD I have going on- I'm just in my thirties and I initially fell ill with fever and joint swelling with pain in my teens.

    I also read a long time ago that viruses can make your ANA turn positive too, even the common cold. That's why it falls in the hands of rheumatologists to sort through this complicated mess.

    This illness along with rampant arthritis runs in my family and I hope I don't pass this on to my kids.

    I'm glad your appt was productive. Hopefully the rheumatologist will rule out anything serious too. Take care
  • Hi,
    I too had a ANA panel done several times and you are right, it sometimes gives a false poss. reading, mine was to determine the poss. of Lupus, and the first test came out poss. however the second was neg. I do have lupus and the reason the second test showed up neg. was because I was no longer in a crisis as I was with the first test. Dont be alarmed though because everyone will be different, you may not have it at all you might have some arthritis acting up, at any rate di get a second test done, and they will sit down with you to explain the process, and what treatments they will use for your diagnosis. Hope this helps you, Good Luck
  • At this point I am not getting too nervous - I have done some looking up and research - and just waiting to hear from the scheduling nurse the date for the tests and appt.

    It is a little curious to me - I already have Graves Disease (remission from 2004) and Ebstien Barr (mono) back when I was finally diagnosed with the Graves (2002). They say you are more at risk if you have contracted an auto immune - they are further checking my thyroid - but believe me I had that checked last fall - and it was negative then - and i have none of the symptoms - you can't miss loss from the thyroid.

    I still seem to wonder if the herniation in my neck has created the stress to bring about the flare up for the antibody test. My doctors seems to feel the muscles are in a state of spasms - constant - for the last 2 + years - but because my reflexes are still good - that it can't be because of the herniation. I have trouble following the logic - but I do understand - oh what a puzzle.

    The pain will not disapate until the mucsles can be turned off....but nothing not even botox injections into the muscles has done that. When I mean they are in spasm - I mean spasms - it is like have neck and upper back spasms 24/7. There has been no one that has treated me (pf, physician, nurses) that haven't been taken back by the state of my muscles.

    What is a girl to do .... hoping that we shall find the right answers so that we can find the solution or at least an improvement.

    thank you all for you input - greatly appreciated.
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