Tried to post this as a new topic before but seems to have disappeared.
I have a left paracentral extrusion at l4/l5 which was diagnosed via ct scan as to the cause of sciatic pain through my left leg. I have been on Lyrica for about one month and am at the maximum daily dose of 600mg. Appears to work and seems to be a better alternative to opiate based pain relief. However on Lyrica I don't feel "all there" and still can't walk or sit for more than 20 or so minutes without pain.
Anyhow whilst Googling the multitude of treatments that exist between a doctor's drug-centric treatment and risk prone surgery I came across this paper http://commons.pacificu.edu/cgi/viewcontent.cgi?article=1479&context=pa
It summarises the results of 2 research studies which trialed intramuscular injections of b12.
The studies have some faults but both showed that b12 injections were beneficial in the treatment of lower back pain. One study here http://www.europeanreview.org/wp/wp-content/uploads/200.pdf
I also came across a few examples of people who believe that they benefit from b12 injections on this forum. Eg http://www.spine-health.com/forum/treatment/pain-management/supplements-nerve-repair
No large long term studies into the use of b12 injections for some reason (possibly no profit motive for pharmaceutical companies to pursue).
One study gave participants an injection every day for 2 weeks (1000mg b12) and the other study 6 injections spread over 2 weeks (500mg).
1 - According to the pharmacist there are no interactions between b12 and Lyrica but has anyone had a reaction to this combination.
2 - Has anyone had a treatment of intramuscular b12 injections for back pain and if so what dosage, frequency and did it make a difference.