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Lyrica for neuropathic pain

AnonymousUserAAnonymousUser Posts: 49,731
edited 06/11/2012 - 8:24 AM in New Member Introductions
I don't know about everyone's experience and I won't try to change anyone's mind. I can only speak for myself.

I have been taking Lyrica for 2+ years for idiopathic peripheral neuropathy in my feet and chronic neck pain from an auto accident. Does it work for me....Hell yes. I cannot do without it three times per day. My current dose is 300mg three times daily. Yup, it is a lot and there are some side effects that I can live with, but without it I can barely stand or turn my neck.

The dose was recommended by a top neurologist at Mayo clinic who has been studying nerve pain for many years and found that Lyrica, in large doses, can provide pain relief with manageable side effects.

The neuropathy has been attributed to the neck injury I suffered about 5 years ago. I have seen many pain specialists who provided some temporary pain relief in my neck, but only Lyrica has given me the relief from the neuropathy to enable me to get around.


  • :) hi! i am on 300mgs a day as well. there are side effects for me such as weight gain, memory problems and just being loopy sometimes. the pain relief i get makes it worth putting up with the side effects. it is the most pain relief i have ever gotten for my sciatica. i am glad it has worked for you as well. of course as with any medication this is best looked after by your doctor. i see this is only your second post. i want to welcome you to the forum. we are here to offer you support and answer what questions we can. please make yourself at home and get a look around at the different forums. good luck with your pain treatment. Jenny :)
  • That is such great news that you have been able to find relief from your pain. Many of us never completely accomplish that.
  • welcome to spine-health...
  • I was up to 600 mg day and it helped but after my epidurals I only had 1 150 mg today so hopefully the epis will help. I got used to the side effects of Lyrica so if I have to go back it's okay. That's interesting the dose is 900 mg a day for you and I thought the max was 600mg. But that's great if it works for you. See you around. Charry
    DDD of lumbar spine with sciatica to left hip,leg and foot. L4-L5 posterior disc bulge with prominent facets, L5-S1 prominent facets with a posterior osteocartilaginous bar. Mild bilateral foraminal narrowing c-spine c4-c7 RN
  • Welcome to the forum. I am a new member also. My insurance company will not cover Lyrica so I have to take 3000mg Neurontin a day plus 100mg Ultram 3 times a day to control my Fibro and foot and back pain. I get to have a nerve conductance test today on my left leg and foot since after my surgery it is half numb and hurts like H!@$ ater walking about 200ft on it. We are all here for the same thing. Hope your Lyrica therapy continues to help. See you in the forum.

    Gary :)))
  • Hi I was on Neurontin for 6 weeks with little effect. I have been on Lyrica for 3 weeks now starting on 100mgs now up to 200mg at night. My sciatic pain has improved slightly. But it has improved my sleeping at night so I am managing 3 or 4 hours good sleep.

    My Gp is going to up my dose soon so hopefully it will work a bit better soon. Does any body have the side effect of forgetting their words I do it's like I know the word but cannot get it out or I call something completely the wrong thing!

    L5/S1 disc herniation
  • :) dawniee, last week i asked my husband what the big white round thing in the refrigerator was? 8} it was a cauliflower and i could not get it out for the life of me. =)) i do think it is a side effect of the Lyrica. hang in there if you can! as the pain relief gets better you will not mind being forgetfull. i think! =D> Jenny :)
  • I was prescribed 50mg 2 per day before my surgery. Before surgery (acdf c 5/6 ) Dr. told me not to take it anymore. Don't really know why. Now my GP has put me back on it 100mg. 2 x day. I try to remember to take it. I do better at night to remember. I honestly have not noticed any difference in the pain. I remember before when I took it I would forget thing & words. I will keep taking them as I have learned here now that it takes some time.
    I welcome any relief & if I get a little "loopy" I'll deal with it I guess. I do not like the idea of weight gain though. We'll see
  • Yes.....I get stuck on a word. Dr said today "It could be the Lyrica....." But, my pain is much less for Sciatica at 300mg/day. Also sleeping better at night. But, in early afternoon and evening I fall asleep sitting up in a chair, or worse, driving. I drop off like a curtain closes..never fell asleep like that before. Dr says if I've been taking the Lyrica in the morning he would not expect the sudden sleeping from the Lyrica, may be something else. But..who knows anymore?
  • I took it for 3 weeks, can't remember the dose, but all it did was make me sleepy.
  • They do consider it minimally invasive but still is major surgery. Had mine done 9-16-08 and my pain in my left lag has gotten worse (not trying to scare you) but does not always get better with time. One piece of friendly advice since this was work related. Do not ever settle on your medical with W/C. I did on my original surgery back in 98 and now I regret it. Just some advice. They have a way of dangling money in your face when your down and strugging to get by. I have a EMG scheduled for today to figure out which nerve is causing my numb foot. Not looking forward to it. Will let everyone know the results when I get them. Hope they figure it out so I can walk more than 100 ft with out pain that causes me to sit down. Keep us posted Sparky. By the way are you an electrician?

    Gary :H
  • OMG i have just sat here for the past ten minutues :))( , i couldnt remember how to spell the word lyrica :B , my daughter had to tell me =)) . When i typed it out it just didnt look right :B . I am clearly losing the plot ~X( . I can tell you what i do , do i stop in mid conversation and totally forget what i was going to say :/ . I get very sleepy too I) . I take 600mg lyrica a day :O , 300 mg in the morning and 300mg at night :? .

    Angie x :H
  • Yes thats me down to a tee!!!! I am constantly stopping mid sentence and cannot find the words for things but I do think the lyrica is helping with the depth of sleep I am getting if not the duration.

    I think my docs going to increase my dose this week so we shall have to wait and see!!! by mid afternoon I am shattered what concerns me is when I finally get back to work I need my wits about me as I am a scrub nurse.

    Dawniee :)
  • Yes I feel better now knowing I am not starting to lose my mind or memory yet. Just reading some of these posts as I take Lyrica also 375-450 mg per day and it is a wonder drug for me because it enables me to walk! My doctor does not seem concerned with the dosage. I also take 200mg Ultram (Tramadol) and Ty 3's .... So sometimes I am a little loopy too but the worst is when I cannot remember words to finish a sentence.
    Nana Shan :H
  • j/k Lyrica as well as epis are helping with the sciatica. Have a good day everyone. Charry
    DDD of lumbar spine with sciatica to left hip,leg and foot. L4-L5 posterior disc bulge with prominent facets, L5-S1 prominent facets with a posterior osteocartilaginous bar. Mild bilateral foraminal narrowing c-spine c4-c7 RN
  • Hi Angie, I notice that you are in the UK - so am I. I'm kind of a newbie here; I was on the old site a couple of years ago but after having discovered Lyrica, managed to get my life back and get back to work ....... although I was never up to much apart from work, home, work, home I was doing pretty well and was quite proud that I had achieved that. I had to take a year off the year before 2006/07 (I was doing temp work) work due to cervical probs, herniated disk, bone spurs, etc etc. Had some cortisone injections, lots of physio, osteopathy, spent lots of money that we couldn't really afford and finally the pain Dr I was seeing prescribed Lyrica which finally worked at my current dosage of 300mg at night. It was like an epiphany - I was sleeping, the muscle spasm subsided and I was functional again.
    However, 2 years down the line I am now experiencing the same old symptoms, it's been increasing since June and I'm wondering if the effects of the Lyrica are no longer the same, if it wears off over time ? Did your dosage increase over time ? I'm sure it did as I started on a very low dose and gradually it was increased, thanks Angie, I'd appreciate any input,
  • It works for me unfortunatelly it seems that i cant be at work and take lyrica.

    Reading the comments that you all posted it started to all make sense, I forget words forget what i said at times, i dont get sleepy from it , i'm trying to take less little by litle but it is mesing with my mood, ALOT.

    Wish me luck with the mission of working towards no more lyrica.
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