:H I have some questions. Do pain meds like vicodin & tramadol cause depression? Or could it be the relentless ongoing pain? Probably both. I'll introduce myself here. Very bad car accident one yr ago, miraculous in that we are all alive (three kids under 8, myself & husband)my injuries the most persistent. Had an mri last week. Will see physiatrist next week to discuss findings. He reluctantly ordered the mri- at my insistence- he has dx'd facet jt syndrome c2,3,& 4 from whiplash. I have daily pain. I take tramadol during the day and vicodin in the late afternoon, evening. Lowest dose becz I am breastfeeding. Pain often leads to migraines. Demoralized, walking through life in survival mode. Any support would be greatly appreciated!