Hi, everyone. I am an Internet engineer, not a pharmacologist. I would like to ask about your experience with generic oral morphine products.
I recently made the mistake of accepting Mallinckrodt Morphine Sulfate ER 30 mg as a generic substitute for MS Contin 30mg. These tablets made me sick. I still had some brand name MS Contin 30 mg (manufactured by Purdue Pharma, and yes, it is expensive) and I went back to the brand name drug, then tried the Mallinckrodt pill, and got even sicker.
Malaise, belching all day, nausea (but not the point of vomiting), stomach and intestines gurgling all day. The next day I took the brand name MS Contin 30 mg, and I felt much better. Better pain relief, no nausea. A little woozy at peak, but I can tolerate woozy; I cannot tolerate nausea all day.
I have found complaints about Mallinckrodt MS ER pills on other web sites. What does Mallinckrodt put in these pills that causes nausea? I called Mallinckrodt and asked that question to one of their pharmacists; there was a long pause before he said he did not know. He is going to send me a list of "inactive ingredients".
Last year I was using Morphine Sulfate CR by Watson Labs. It was as good as brand name MS Contin. I called Watson Pharmaceutical to find out where I could buy it this year. Watson rep told me they had stopped manufacturing morphine.
Several years ago CVS filled these prescriptions with MSER from Ethex. However, last year Ethex pleaded guilty to two felonies for not reporting manufacturing problems to the FDA. According to what I read, the parent company KV Pharmaceuticals closed Ethex.
Apparently Mallinckrodt is selling their inferior product into the void left by the withdrawal of Ethex and Watson from the market.
I am trying an off-green Morphine Sulfate ER 30 mg Endo tablet, which is available at one local pharmacy.
I would be interested in knowing more about the experiences of other people who get scripts for MS Contin. Have you used a generic MSER tablet from another manufacturer that was satisfactory?