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What's the best Muscle Relaxant accessible with a solution? All sentiments needed!

I'm about to start a Skeletal Muscle Relaxant for Physical Therapy and need your help! Here are a list of Skeletal Muscle Relaxants. Please select the one you have had the best results with and let me know about it! I would appreciate it so much! Thanks in advance!

-Carisoprodol (Soma) 
-Cyclobenzaprine (Flexeril)
-Metaxalone (Skelaxin)
-Tizanidine (Zanaflex) 
-Dantrolene (Dantrium)
-Baclofen (Lioresal)
-Chlorzoxazone (Paraflex)
-Orphenadrine (Norflex)



  •  After trying several over the years, I've found that Baclofen works the best for me. Keep in mind everyone is different though. Doctors don't prescribe Soma much anymore. Skelaxin is supposed to cause less drowsiness but I found it not as effective. Flexeril kept me up all night and didn't do much for the spasms. 
    Ol' Spiney..Micro-D L4-L5, TLIF L4-S1 -post op central HNP L4-S1,stenosis, retrolisthesis, EF, facet arthropathy, lumbar& cervical DDD. FBSS- Medtronic pain pump & SCS
  • WLLadyWLLady Ontario CanadaPosts: 1,331
    i have had the same experience as medey.  flexeril kept me up all night....baclofen has worked the best for me too. 
    Spine-Health Moderator
    Dec '16 T10-S2 fusion with pelvic fixation. Laminectomies L2, L3, L4, L5, facet removal, cages L4-5, L5-S1, severe scoliosis, arthritis and stenosis repair. 

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  • dilaurodilauro ConnecticutPosts: 12,891
    Over the years, here is my run down on muscle relaxers

    Methocarmbonal (Rhobaxin)  -  Didnt get much from this, except my eye muscles were too relaxed
    Flexeril -  For me too much, the next day I felt like I had a major hangover that lasted a full day
    Soma -  Effective, no real room for dosage changes, can be very addictive, doctors do not like to prescribe
    Zanaflex -  Very effective.  Total relaxation.  But perhaps too much, had me way to drowsy
    Baclofen - For me the best, wide range of dosages and taken as prescribed helps with total relaxation.

    Ron DiLauro Veritas-Health Forums Manager
    I am not a medical professional. I comment on personal experiences 
  • AkiraAAkira Redlands, CAPosts: 82
    Soma, but the PM doctor will not prescribe it anymore.
  • I agree with Meyday. Baclofen is wonderful, but I can only handle it at night. I take Skelaxin during work hours.
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  • Sheri76Sheri76 Michigan Posts: 639
    I was given methocarbomal after my surgery, but I felt they were making me kinda sick. Zanaflex didn't help any.

     Flexeril seems to work best for me. I only take it at night because it helps me sleep. When I go a night without taking it I get muscle cramps in lower lumbar, hips legs, and feet. I haven't ever felt like it was too much...doesn't make me feel wacked out in the morning, but maybe I'm wacky normally and can't tell the difference ; )
  • itsautonomicitsautonomic LouisianaPosts: 2,561
    Baclofen as well after being on many, I have no side effects and it has a subset that works somewhat on nerve pain.  My doctors tell me its the go to for spinal cord issues, it does not sound like you have that though.
    Do your due dilegence, trust you know your body and question everything if it does not fit. Advocate for yourself and you will be suprised what will be revealed trusting your body and instinct.
  • Skelaxin was only mildly effective. No major side effects. Too high a copay on my insurance.

    Cyclobenzaprine (flexaril) didn't help much. After a couple months it didn't work at all.

    Baclofen worked moderately well, but the side effects, for me, were horrendous. It made me moody and forgetful. I couldnt communicate right. I couldn't come up with the words I wanted in basic conversations. Had to discontinue it.

    I've been using Tizanidine for maybe a year. It works pretty well for muscle spasms. The side effects are a little difficult, but I manage.  It makes my mouth extremely dry. No matter how much water I drink, it never completely gets better. Depending on dose, it also makes me tired. My dose is between 4-8 mg at a time. 8mg makes me very sleepy. Also, I ran  into an issue with tizanidine I had to ask pharmacist about. If you take it with coffee, the amount of tizanidine in your blood increases. For example, if i drink coffee and take an 8mg dose of tizanidine at the same time, I will not be able to stay awake / conscious. And I am not overly sensitive to medications.  So take the lowest dose you can if you use this, and be mindful of when you drink coffee with it.
    Hope this helps!
  • Muscle relaxant medicines relax muscles and may help reduce pain in people who have muscle spasms. The muscle-relaxing effects of these medicines are most likely the result of their ability to depress the central nervous system.
    I have also get some other details on mygenericpharmacy

  • Zanaflex

     was too strong for me..out like a lite in 5 min or less..dangerous to me... as i would suddenly wake up and not realise i had done so


     was my workable solution as i felt almost normal and was able to work


     did squat


    Put me out but would wake in pain

    William Garza
    Spine-Health Mod

    Welcome to Spine-Health

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