Injections

Potential Risks and Complications of Prolotherapy

By: Vert Mooney, MD and Bjorn Eek, MD
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The injection technique involved in prolotherapy requires skill and care on the part of the physician. Training and experience are important.

Possible side effects may last a few days to a couple weeks and include:

  • Swelling

  • Intense pain and stiffness

  • Headache

  • Allergic reaction

Reports of more serious complications have been rare, but could include:

  • Spinal fluid leak

  • Permanent nerve damage or paralysis

  • Pneumothorax

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Vert Mooney, MD Bjorn Eek, MD
January 25, 2000