Posterolateral vs. Interbody Fusion: The Two Main Approaches to Spinal Fusion


Fig. 1: Bone graft site for a posterolateral fusion
(Larger view)


Fig. 2: Side view of lumbar spine
(Larger view)


Fig 3: Oblique (slanted) view
of lumbar spine
(Larger view)


Fig 4: Two level spine fusion
(six screws and two rods)
(Larger view)



Fig 5: One-level spine fusion
(four screws and two rods)
(Larger view)

In general, there are two main approaches to spinal fusion, a surgery designed to stop low back pain caused by painful motion of the vertebrae. One of the main differences between these two approaches is where the bone graft is laid in the spine to form the fusion.

Posterolateral Fusion:

The graft to form the bony bridge can be placed between the transverse processes (shaded area in Figure 1) in the back of the spine. This will allow the bone to heal from the transverse process of one vertebra to the transverse process of the next vertebra. This type of spine fusion is called a posterolateral fusion.

The most common fixation technique employed in a posterolateral fusion is pedicle screw fixation. This refers to placing screws within the pedicles (Figure 2, Figure 3) of each vertebral segment (bilaterally—on both sides of the spine) and connecting them to each other with a metal rod. A one level fusion would fuse two vertebrae and usually uses four screws and two rods. A two level fusion fuses three vertebrae and uses six screws and two rods (Figure 4, Figure 5).

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Interbody Fusion:

In an interbody spine fusion, the bone graft is placed in between the vertebral bodies where the disc usually lies. The disc has to be completely removed and endplates cleaned prior to placement of the graft. This will allow the fusion to occur from one vertebral body to the other through their endplates (red lines on Figure 2). The graft can be placed in between the vertebral bodies into an interbody position through an anterior approach (from the front) with an incision in the abdomen. This approach is called an Anterior Lumbar Interbody Fusion, or ALIF. The graft can also be placed from a posterior approach through the back. This approach is called a Posterior Lumbar Interbody Fusion or PLIF, or Transforaminal Lumbar Interbody Fusion or TLIF. One difference between a TLIF and PLIF is the angle at which the disc is approached, but both procedures are done through an incision in the patient’s back.

Bone grafts are commonly placed within cages that hold the graft and resist the compressive forces of the vertebrae.

More Interbody Fusion Videos:

ALIF Video

PLIF Video

TLIF Video

  • Material: These cages are made of different materials, such as Titanium, Poly Ethyl Ethyl Ketone (PEEK) which resembles a very tough plastic, or Carbon Fiber (similar to PEEK). The latter two have the advantage of being able to show the status of the bone inside them on X-ray, facilitating the assessment of whether a fusion has occurred. Titanium cages are stronger, but make the radiographic assessment more difficult. In addition to synthetic cages, Cortical bone cages, which are stronger than the graft but not as strong as the synthetic cages, can also be used as a cage. The advantage of cortical bone cages is that eventually the cage itself can incorporate into the fusion as well.
  • Shape: The shape of the cage is a function of the approach that it is used for. The cages for ALIF's are generally larger and more round shaped. The cages for a PLIF are generally more rectangular shaped. The cages for TLIF's are most commonly boomerang shaped or rectangular shaped.

The advantage to an interbody fusion over a posterolateral fusion is the increased surface area for bone contact and the ability of the graft to share the load on the anterior (front) portion of the spine (anterior column support). These factors usually translate to a more favorable fusion rate. The application of both techniques, an interbody fusion in addition to a posterolateral fusion, theoretically affords the highest chances for a fusion (similar to the use of belt and suspenders). This type of surgery is commonly referred to as a 360-degree fusion.

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